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Related Concept Videos

Stress Prevention and Stress Management Techniques III01:25

Stress Prevention and Stress Management Techniques III

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Regular exercise and meditation serve as essential tools in managing stress and promoting physical and mental well-being.
The Role of Exercise in Stress Management
Regular physical activity is essential for reducing stress and promoting cardiovascular health. Exercise strengthens the heart, enhances blood flow, keeps blood vessels flexible, and helps lower blood pressure, all of which reduce the body's stress response. Research shows that adults who exercise regularly have nearly half the...
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Physiological Foundation of Stress01:24

Physiological Foundation of Stress

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Stress triggers a coordinated physiological response involving the sympathetic nervous system (SNS) and the hypothalamic-pituitary-adrenal (HPA) axis. This dual activation ensures that the body is prepared for both immediate and prolonged stress management. The process begins with the perception of a stressor. This initial phase activates the SNS, leading to the rapid release of adrenaline (epinephrine) from the adrenal glands.
Role of the Sympathetic Nervous System
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Altered States of Awareness01:06

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Altered states of consciousness represent significant deviations from one's normal mental state. These deviations can range from subtle changes in awareness to profound transformations in perception, thought processes, and sensory experiences. Altered states of consciousness can be triggered by various factors, including drug use, meditation, hypnosis, illness, or even intense fatigue.
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Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
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Corrigendum to "Functioning assessment short test for autism (FAST-A): a tool to evaluate adaptive functioning in autistic adults" [European Neuropsychopharmacology, 112, 112887].

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Related Experiment Video

Updated: Sep 17, 2025

Using a Murine Model of Psychosocial Stress in Pregnancy as a Translationally Relevant Paradigm for Psychiatric Disorders in Mothers and Infants
06:39

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Mindfulness-based stress reduction intervention during pregnancy changes maternal brain.

Yvan Gomez1, Ayako Nakaki2,3,4, Allegra Conti5

  • 1BCNatal Fetal Medicine Research Center (Hospital Clínic and Hospital Sant Joan de Déu), Universitat de Barcelona, Barcelona, Spain.

Scientific Reports
|July 2, 2025
PubMed
Summary
This summary is machine-generated.

Mindfulness-Based Stress Reduction during pregnancy positively impacts maternal brain structure, increasing frontal lobe surface area and altering brain metabolites. This intervention shows significant neurobiological effects in expectant mothers.

Keywords:
BrainMRIMindfulness-based stress reductionPregnancyProton magnetic resonance spectroscopySmall-for-gestational age

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Profiling Maternal Behavior Responses During Whole-Brain Imaging
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Area of Science:

  • Neuroscience
  • Psychiatry
  • Radiology

Background:

  • Pregnancy is associated with significant neurobiological changes.
  • Maternal stress during pregnancy can negatively impact both maternal and fetal outcomes.
  • Mindfulness-Based Stress Reduction (MBSR) is a potential intervention to mitigate stress.

Purpose of the Study:

  • To evaluate the effect of an 8-week Mindfulness-Based Stress Reduction (MBSR) program on maternal brain structure and metabolism during pregnancy.
  • To analyze differences in cortical morphometry and brain metabolite concentrations between pregnant women in an MBSR group and a usual care group.

Main Methods:

  • Secondary analysis of the IMPACT BCN randomized clinical trial.
  • Magnetic resonance imaging (MRI) including cortical surface area analysis and proton magnetic resonance spectroscopy (¹H-MRS) in the third trimester.
  • Assessment of mindfulness using the Five Facet Mindfulness Questionnaire (FFMQ).

Main Results:

  • MBSR participants showed significantly larger surface areas in the right superior frontal region compared to the usual care group.
  • ¹H-MRS revealed higher concentrations of myo-inositol in the MBSR group.
  • Higher mindfulness scores (non-judgmental, non-reactivity) correlated with larger right superior frontal areas.

Conclusions:

  • The MBSR program during pregnancy significantly influences maternal brain structure, specifically increasing frontal lobe surface area.
  • MBSR is associated with changes in maternal brain metabolite concentrations, such as myo-inositol.
  • Mindfulness practices during pregnancy may promote positive neuroplasticity in the maternal brain.