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Updated: Sep 17, 2025
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Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
Published on: August 25, 2021
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Exploring computerized tomography findings and ocular trauma score in open globe injuries: assessing imaging's
Ezgi Karataş1, Denizcan Özizmirliler2, Ceren Durmaz Engin3
1Department of Ophthalmology, Faculty of Medicine, Ibrahim Cecen University, Agri, Turkey. e.karatas.2015@gmail.com.
BMC Ophthalmology
|July 2, 2025
Summary
Computerized tomography (CT) findings correlate with the severity of open globe injuries (OGI). Specific CT indicators like scleral irregularity and abnormal vitreous density are linked to worse outcomes on the Ocular Trauma Score (OTS).
Area of Science:
- Ophthalmology
- Medical Imaging
- Trauma Surgery
Background:
- Open globe injury (OGI) is a severe ocular trauma requiring accurate prognostic assessment.
- The Ocular Trauma Score (OTS) is a validated tool for predicting visual outcomes in OGI.
- Computerized tomography (CT) provides detailed anatomical information but its correlation with OGI severity, as measured by OTS, needs further investigation.
Purpose of the Study:
- To investigate the relationship between specific computerized tomography (CT) findings and the Ocular Trauma Score (OTS) in patients with open globe injury (OGI).
- To evaluate the prognostic value of CT imaging in assessing the severity of ocular trauma.
Main Methods:
- A retrospective study included 123 patients diagnosed with OGI.
- CT scans were analyzed for scleral irregularity, reduced globe volume, dislocated crystalline lens, aberrant vitreous density, chorioretinal thickening, and presence of foreign body/air.
- The association between CT findings and OTS categories was assessed using multivariate analysis.
Main Results:
- The most common OTS category was stage 3 (57.7%). Prevalent CT findings included severe scleral irregularity/globe collapse (34.1%), dislocated crystalline lens (33.3%), and abnormal vitreous density (26.8%).
- Severe scleral irregularity/globe collapse (OR=1.36) and abnormal vitreous density (OR=1.7) were significantly associated with more advanced OTS stages (I or II).
- The presence of three or more CT findings strongly predicted more severe OTS stages (OR=6.82), while absence of CT findings predicted less severe stages (OR=0.05).
Conclusions:
- CT imaging findings are valuable for correlating with the severity of open globe injuries.
- CT plays a crucial role in the comprehensive assessment and prognostic evaluation of ocular trauma.
- These imaging findings can aid clinicians in better understanding the extent of injury and predicting patient outcomes.
