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Updated: Sep 17, 2025

Anterior Segment Organ Culture Platform for Tracking Open Globe Injuries and Therapeutic Performance
Published on: August 25, 2021
Exploring computerized tomography findings and ocular trauma score in open globe injuries: assessing imaging's
Ezgi Karataş1, Denizcan Özizmirliler2, Ceren Durmaz Engin3
1Department of Ophthalmology, Faculty of Medicine, Ibrahim Cecen University, Agri, Turkey. e.karatas.2015@gmail.com.
Background:
To investigate the relationship between computerized tomography (CT) findings and the Ocular Trauma Score (OTS) in patients with open globe injury (OGI).
Methods:
This study included 123 individuals with OGI, examining injury characteristics, clinical symptoms, and CT scans for scleral irregularity, reduced globe volume, dislocated crystalline lens, aberrant vitreous density, chorioretinal thickening, and foreign body/air presence. The prognostic value of CT imaging in OGI was evaluated by assessing its relationship with OTS findings.
Results:
The most common OTS category was stage 3, found in 71 eyes (57.7%). The prevalent CT findings included severe scleral irregularity or globe collapse (34.1%), dislocated crystalline lens (33.3%), and abnormal vitreous density (26.8%). Multivariate analysis revealed that severe scleral irregularity or globe collapse (Odds Ratio [OR] = 1.36, p = 0.006) and abnormal vitreous density (OR = 1.7, p < 0.001) were significantly associated with more advanced OTS stages (I or II), indicating more severe ocular trauma. The presence of three CT findings was associated with a higher likelihood of falling into OTS stages I or II (OR = 6.82, p = 0.001). Conversely, the absence of CT findings was associated with a decreased probability of having more severe OTS stages (OR = 0.05, p < 0.001).
Conclusions:
The study concludes that imaging findings are valuable for correlating with the severity of open globe injuries, highlighting the importance of CT in assessing ocular trauma.

