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Brain targeted lipid nanoparticles with Hv1 inhibitors alleviate neuroinflammation post-ischemic stroke

Zeyu Yang1, Lei Jin1, Longxiang Li1

  • 1Neurosurgery Center, Department of Cerebrovascular Surgery, The Engineering Technology Research Center of Education Ministry of China on Diagnosis and Treatment of Cerebrovascular Disease, Guangdong Provincial Key Laboratory on Brain Function Repair and Regeneration, The Neurosurgery Institute of Guangdong Province, Zhujiang Hospital, The National Key Clinical Specialty, Southern Medical University, Guangzhou, 510282, China.

Journal of Nanobiotechnology
|July 2, 2025
PubMed
Abstract

Keywords:
Brain-targeted LNPIschemic strokeMicroglialNeuroinflammationVoltage-gated proton channel Hv1

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