Attitudes and acceptance of mRNA-based vaccine for neglected tropical diseases: A multi-country study in Asia
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View abstract on PubMed
Summary
This summary is machine-generated.Willingness to receive mRNA vaccines for neglected tropical diseases (NTDs) varies across Asia. Higher knowledge and positive attitudes significantly increase acceptance, while concerns about side effects decrease it.
Area Of Science
- Vaccinology
- Public Health
- Epidemiology
Background
- Neglected tropical diseases (NTDs) pose a significant global health burden.
- Messenger RNA (mRNA) vaccine technology offers a novel approach for disease prevention.
Purpose Of The Study
- To investigate the willingness to receive mRNA-based vaccines against NTDs in several Asian countries.
- To identify factors influencing vaccine acceptance, including knowledge, attitudes, and demographics.
Main Methods
- An anonymous cross-sectional survey was conducted in five Asian countries between June and December 2023.
- The survey assessed knowledge and attitudes towards mRNA vaccines and their impact on vaccination acceptance for NTDs.
Main Results
- Willingness to receive mRNA-based NTD vaccines was associated with higher knowledge scores (aOR=2.61).
- Bangladesh reported the highest willingness (51.4%), while Pakistan and India reported the lowest.
- Understanding mRNA vaccine mechanisms and perceived advantages positively correlated with acceptance; concerns about side effects and traditional methods showed negative correlation. Younger age and female gender were associated with greater acceptance.
Conclusions
- Knowledge and positive attitudes are crucial for promoting mRNA-based NTD vaccine uptake in Asia.
- Addressing concerns about side effects and highlighting advantages like rapid development are key strategies.
- Targeted interventions focusing on younger demographics and females may enhance vaccination acceptance.
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