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Updated: Sep 17, 2025

Synthesis of a Borylated Ibuprofen Derivative Through Suzuki Cross-Coupling and Alkene Boracarboxylation Reactions
Published on: November 30, 2022
Awareness of the use of non-steroidal anti-inflammatory drugs: A cross-sectional study
Lasha Chkhikvadze1, Elisabed Chikobava1, Nithesh Hariharan1
1American MD Program, Tbilisi State Medical University, 0186 Tbilisi, Georgia.
Abstract:
Non-steroidal anti-inflammatory drugs (NSAIDs) are widely utilized across the globe and are frequently used without prescription for various therapeutic purposes. Given their potential for severe adverse effects, assessing the awareness of the use of NSAIDs is crucial. The present study evaluated the awareness levels of the use of NSAID among consumers through a descriptive, cross-sectional, non-randomized study. A 33-item online survey was conducted with 385 NSAID consumers aged ≥18 years between August and October, 2023. Awareness levels were determined based on knowledge and attitude scores assigned to correct responses. The results revealed that headaches (62.9%) and menstrual pain (32.4%) were the primary reasons for the use of NSAIDs, with ibuprofen being the preferred generic NSAID. The overall knowledge of NSAIDs was found to be inadequate, particularly concerning associated risks, such as stroke and myocardial infarction, despite a good understanding of the gastrointestinal risks. Female participants, those aged 26-45 years, and individuals with higher education levels demonstrated better knowledge. A concerning tendency toward self-administration and over-the-counter use was observed. These findings highlight the need for targeted educational initiatives and regulatory interventions to improve NSAID awareness and promote responsible medication practices.
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