Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Peripherally and Centrally Acting Muscle Relaxants: A Comparison01:09

Peripherally and Centrally Acting Muscle Relaxants: A Comparison

3.7K
Skeletal muscle relaxants can target the central nervous system [CNS] to reduce muscle tension or act directly at the neuromuscular junction to induce temporary paralysis. These two classes of muscle relaxants are called centrally acting muscle relaxants and peripherally acting muscle relaxants. They differ in their action, mechanism, administration route, and clinical uses.
Centrally acting muscle relaxants can be further divided into spasmolytic and antispasmodic drugs. Spasmolytic...
3.7K
Motor Unit Stimulation01:20

Motor Unit Stimulation

2.0K
When the neuron of a motor unit fires an action potential, it triggers a series of events, leading to a twitch contraction in the muscle fibers. The process of excitation-contraction coupling is crucial in relaying the action potential to the muscle fibers.
The latent period of contraction marks the onset of excitation-contraction coupling, when the action potential propagates across the sarcolemma, preparing the muscle fibers for contraction. As the fibers enter the contraction phase, the...
2.0K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Treatment Satisfaction, Improvements in Jawline Definition, and Psychosocial Impact With OnabotulinumtoxinA for Platysma Prominence: Patient-Reported Outcomes From 2 Multicenter, Randomized, Placebo-Controlled Phase 3 Studies.

Aesthetic surgery journal·2026
Same author

Socially Transformative Aesthetics: Real-World Evidence of Positive First Impressions After Pan-Facial Aesthetic Treatments.

Aesthetic surgery journal. Open forum·2026
Same author

Regenerative Aesthetics: Present Advances and Emerging Strategies for Optimized Tissue Health.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]·2026
Same author

A Randomized, Double-Blinded Pilot Study Comparing Synthetic Versus Human-Derived Topical Epidermal Growth Factor for Facial Rejuvenation and Psychosocial Perception.

Journal of cosmetic dermatology·2026
Same author

Measuring Facial Appearance in GLP-1 Agonist Use with the FACE-Q Aesthetics Item Library.

Aesthetic surgery journal·2026
Same author

Neuroaesthetics: Evolutionary Thinking in Facial Aesthetic Medicine.

Journal of cosmetic dermatology·2026
Same journal

Laser and Energy-Based Devices in Aesthetic Practice: A 10-Year Single-Surgeon Review of Treatments, Complications, and Same-Practice Surgical Crossover.

Aesthetic surgery journal. Open forum·2026
Same journal

Revisiting the Health Insurance Portability and Accountability Act: Practical Applications for the Modern Plastic Surgeon.

Aesthetic surgery journal. Open forum·2026
Same journal

From Nose Job to a Better Job: A Scoping Review of Facial Aesthetics, Attractiveness Bias, and Outcomes in the Workplace.

Aesthetic surgery journal. Open forum·2026
Same journal

Correction to: Redefining Neck Rejuvenation: The Novel Hyoid-to-Mastoid Crevasse Neo-Ligament and OnderKaak Angle in Deep Plane Neck Lift.

Aesthetic surgery journal. Open forum·2026
Same journal

Response by Jabbaripour Sarmadian to "Autologous Fat Grafting Combined With Platelet-Rich Plasma in the Treatment of Female Genitourinary Aging: A Retrospective Study" by Ren et al.

Aesthetic surgery journal. Open forum·2026
Same journal

Determining the Position, Morphology, and Location of the Depressor Anguli Muscle Through Ultrasound in the Caucasian Population.

Aesthetic surgery journal. Open forum·2026
See all related articles

Related Experiment Video

Updated: Sep 17, 2025

A Simple Non-invasive Method for Temporary Knockdown of Upper Limb Proprioception
07:42

A Simple Non-invasive Method for Temporary Knockdown of Upper Limb Proprioception

Published on: March 3, 2018

9.6K

Neuromodulator Co-Administration With a Vibration Device: Patient Comfort Study.

Steven Dayan, Nimit Gandhi, Catherine Carvajal

    Aesthetic Surgery Journal. Open Forum
    |July 2, 2025
    PubMed
    Summary
    This summary is machine-generated.

    Botulinum toxin injections can be painful, but using a vibration device during the procedure significantly reduces patient discomfort. Most patients preferred the vibration method, indicating improved comfort during aesthetic treatments.

    More Related Videos

    A Method for Evaluating Timeliness and Accuracy of Volitional Motor Responses to Vibrotactile Stimuli
    07:28

    A Method for Evaluating Timeliness and Accuracy of Volitional Motor Responses to Vibrotactile Stimuli

    Published on: August 2, 2016

    7.4K
    Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
    04:29

    Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression

    Published on: January 7, 2019

    28.9K

    Related Experiment Videos

    Last Updated: Sep 17, 2025

    A Simple Non-invasive Method for Temporary Knockdown of Upper Limb Proprioception
    07:42

    A Simple Non-invasive Method for Temporary Knockdown of Upper Limb Proprioception

    Published on: March 3, 2018

    9.6K
    A Method for Evaluating Timeliness and Accuracy of Volitional Motor Responses to Vibrotactile Stimuli
    07:28

    A Method for Evaluating Timeliness and Accuracy of Volitional Motor Responses to Vibrotactile Stimuli

    Published on: August 2, 2016

    7.4K
    Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression
    04:29

    Vagus Nerve Stimulation As an Adjunctive Neurostimulation Tool in Treatment-resistant Depression

    Published on: January 7, 2019

    28.9K

    Area of Science:

    • Aesthetics
    • Dermatology
    • Pain Management

    Background:

    • Neuromodulator injections, like botulinum toxin, are common cosmetic procedures.
    • Pain is a frequent side effect associated with these injections.
    • Improving patient comfort during injections is a clinical goal.

    Purpose of the Study:

    • To evaluate the efficacy of a vibration device in reducing pain during botulinum toxin injections.
    • To assess patient comfort and treatment experience with and without vibration assistance.
    • To determine patient preference for vibration-assisted versus non-assisted injections.

    Main Methods:

    • A single-center, randomized, split-face, controlled study was conducted.
    • Botulinum toxin A was administered for glabellar lines with and without a vibrating beauty bar.
    • Pain was measured using a visual analog scale, and patient questionnaires were used.

    Main Results:

    • Mean pain scores were lower with vibration (4.0) compared to without (4.9).
    • A significant majority of patients (81.7%) preferred vibration for subsequent injections.
    • Patients reported a positive perception and improved comfort with the vibration device.

    Conclusions:

    • Pairing a vibration device with aesthetic botulinum toxin injections reduces pain and improves patient comfort.
    • Vibration therapy is a simple and effective adjunct for enhancing patient experience during cosmetic injections.
    • The findings support the routine use of vibration devices to mitigate injection-related pain.