Related Experiment Video
Updated: Sep 17, 2025

Assessing Changes in Volatile General Anesthetic Sensitivity of Mice after Local or Systemic Pharmacological Intervention
Published on: October 16, 2013
Comparative effect of bupivacaine local anesthesia with ropivacaine present with fentanyl
Aman Gour1, Vishwas Manohar Joshi1, Jamale P B1
1Department of Anesthesiology, Krishna Institute of Medical Sciences, Krishna Vishwa Vidyapeeth (Deemed To Be University), Karad, Maharashtra, India.
Abstract:
Local anesthetics for lower limb anesthesia frequently use ropivacaine and bupivacaine due to their unique pharmacological properties. The point of this study was to look at how well efficacy of hyperbaric 0.5% bupivacaine with fentanyl and hyperbaric 0.75% ropivacaine with fentanyl worked in spinal anesthesia and compare and talk about them. Each group evaluated a total of 30 patients using various parameters to assess side effects and complications. We found among patients receiving bupivacaine, 70.0% did not require rescue medication, whereas 30.0% did. In contrast, among patients receiving ropivacaine, 86.7% did not require rescue medication, while 13.3% did. Thus, found non-significant difference. Bupivacaine has a faster onset and longer duration of sensory block and motor block, providing better early pain alleviation than ropivacaine.
Related Concept Videos
Local Anesthetics: Clinical Application as Epidural Anesthesia
Since epidural anesthetics can be infused through an epidural catheter, all types of drugs, including short-acting ones, can be administered. Chloroprocaine and lidocaine are examples of short and long-duration anesthetics, respectively. Bupivacaine...
Local Anesthetics: Common Agents and Their Applications
Cocaine is an ester of benzoic acid and methylecgogine. It is used to anesthetize and vasoconstrict locally. Currently, it is used primarily for topical applications. It is beneficial for surgeries on the upper respiratory tract, providing anesthesia and shrinking the mucosa. Cocaine in the form of cocaine hydrochloride is...
Local Anesthetics: Pharmacokinetics
Local Anesthetics: Clinical Application as Surface, Infiltration, and Conduction Block Anesthesia
Local Anesthetics: Clinical Application as Spinal Anesthesia
Local Anesthetics: Differential Sensitivity of Nerve Fibers

