A successful method of administering cyclosporin A to the chacma baboon

Cyclosporin A (CYA) is a powerful immunosuppressant. Hitherto, it has proved difficult to maintain therapeutic whole-blood levels of the drug in the chacma baboon, making this animal unsuitable for transplantation studies if CYA is used. A successful method of maintaining adequate therapeutic levels after the intramuscular injection of CYA in a mixture of alcohol and Intralipid (Saphar) is described.