Advancements in gas chromatography-ion mobility spectrometry for analysing natural medicines
Yanan Xu1, Ruien Li2, Lequn Zhang1
1Northeast Asia Research Institute of Traditional Chinese Medicine, Changchun University of Chinese Medicine, 1035 Boshuo Road, Changchun 130117, China. baixy1212@163.com.
Abstract:
Gas chromatography-ion mobility spectrometry (GC-IMS) is an emerging analytical technique with significant potential for natural medicine analysis because of its high sensitivity, resolution, rapid detection, and portability. This article discusses the principles of GC-IMS technology and its diverse applications in analysing natural medicine compositions. These applications encompass authenticity, origin, matrix, quality determination, and identification of volatile compounds. Additionally, the potential of combining GC-IMS with other analytical techniques is investigated. Finally, the current challenges facing the adoption of GC-IMS for natural medicine discovery and characterisation are presented alongside future development directions. This article primarily aims to provide a comprehensive reference for applying GC-IMS technology in the analysis of natural medicine components and foster continued advancements in natural medicine research.
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