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SomaScan Bioinformatics: Normalization, Quality Control, and Assessment of Pre-Analytical Variation

Julián Candia1

  • 1Longitudinal Studies Section, Translational Gerontology Branch, National Institute on Aging, National Institutes of Health, Baltimore, MD, USA. julian.candia@nih.gov.

Methods in Molecular Biology (Clifton, N.J.)
|July 2, 2025
PubMed
Abstract

Keywords:
BioinformaticsNormalizationPAVPre-analytical variationQCQuality controlSomaScanSomaSignal Test

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Sample preparation is an essential step in the analytical process. It involves preparing a sample so that it can be analyzed accurately. The goal is to extract the analyte, the substance you want to measure, from the sample while removing any components that may interfere with the analysis. Sample preparation techniques vary depending on the physical state of the sample.
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