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DiffCNN: A collaborative framework of diffusion model and CNN for semi-supervised medical image segmentation.

Shanshan Xu1, Lixia Tian2

  • 1School of Computer Science and Technology, Beijing Jiaotong University, Beijing, 100044, China; Beijing Key Laboratory of Traffic Data Analysis and Mining, Beijing Jiaotong University, Beijing, 100044, China.

Neural Networks : the Official Journal of the International Neural Network Society
|July 2, 2025
PubMed
Summary
This summary is machine-generated.

This study introduces DiffCNN, a novel framework for semi-supervised medical image segmentation. DiffCNN combines diffusion models and CNNs to improve segmentation accuracy, especially with noisy images.

Keywords:
Adversarial learningCollaborative trainingTeacher-student frameworkTransformer

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Area of Science:

  • Medical Imaging
  • Artificial Intelligence
  • Computer Vision

Background:

  • Teacher-student architectures are common in semi-supervised medical image segmentation.
  • Existing methods face challenges with teacher subnet optimization and handling noisy images due to CNN limitations.

Purpose of the Study:

  • To propose DiffCNN, a collaborative framework using diffusion models and CNNs for improved semi-supervised medical image segmentation.
  • To address limitations of traditional teacher-student architectures in noisy medical image segmentation.

Main Methods:

  • DiffCNN employs distinct CNN and diffusion subnets for collaborative learning.
  • The diffusion subnet learns mask distributions to mitigate noise.
  • Adversarial learning enhances the diffusion subnet's performance by aligning with real masks.

Main Results:

  • DiffCNN demonstrates superior performance compared to state-of-the-art methods on three medical image segmentation datasets.
  • The collaborative framework effectively extracts complementary information and handles noisy images.

Conclusions:

  • DiffCNN offers a robust and effective approach for semi-supervised medical image segmentation.
  • The integration of diffusion models and CNNs presents a promising direction for medical image analysis.