Rational design and facile preparation of porous polymer functionalized magnetic composite for high performance...

Efficient isolation and enrichment are essential in the sensitive and accurate monitoring of estrogens residuals in complex samples. In this connection, according to the chemical properties of the selected estrogens, N-vinyl carbazole/1-allyl-3-methylimidazole chloride were selected as mixed functional monomers to prepare a new porous polymer functionalized magnetic composite (PPMC) through convenient one-pot preparation strategy and employed as the adsorbent of magnetic solid phase extraction (MSPE). Density functional theory was adopted to analyze the selection of functional monomers. The adsorption behaviors and removal mechanism were investigated thoroughly based on batch experiments. Under the beneficial adsorption and desorption conditions, the introduced PPMC/MSPE exhibited superior capture performance towards analytes by multiple interactions. Combining PPMC/MSPE with HPLC/DAD, trace analysis approach for the investigated estrogens in milk and environmental waters was developed. The method presented high sensitivity (limits of detection were 0.0068-0.088 μg/L and 0.028-0.30 μg/kg for water and milk samples, respectively), good precision (RSDs of 0.71-9.4 %) and satisfactory spiked recoveries (80.7-116 %). Moreover, accuracy of the suggested method was inspected with confirmatory experiments. The established PPMC/MSPE technique overcomes the dilemmas existing in the extraction of estrogens and the developed approach exhibits wide potential in the monitoring of estrogens residuals in food and aqueous samples.