Allantoinase and allantoicase synthesis in Pseudomonas aerguinosa
Abstract:
Allantoinase (allantoin amidohydrolase, EC 3.5.2.5.) and allanoicase (allantoate amidinohydrolase, EC 3.5.3.4) of Pseudomonas aeruginosa are inducible enzymes, whose syntheses are enhanced by the presence of allantoin, allantoate, ureidoglycolate, N-carbamoyl-L-asparagine, N-carbamoyl-L-aspartate, hydantoate, and diureidomethane. For each compound a specific ratio between the activities of allantoinase and allantoicase was obtained. The synthesis of these enzymes is not coordinately controlled. N-Carbamoyl-L-aspartate, hydantoate, and diureidomethane are gratuitous inducers.
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