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Updated: Sep 17, 2025

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Regulation of neuronal ankyrin localization and function by post-translational modifications.

Kalynn M Bird1, Paul M Jenkins1,2

  • 1Department of Pharmacology, University of Michigan Medical School, Ann Arbor, MI, U.S.A.

Biochemical Society Transactions
|July 3, 2025
PubMed
Summary

Ankyrins are crucial scaffolding proteins in neurons. Post-translational modifications like phosphorylation regulate their localization and function, potentially impacting neurological diseases such as epilepsy and autism.

Keywords:
ankyrinneurodevelopmental disorderspalmitoylationphosphorylationprotein localizationubiquitinationvoltage-gated sodium channel

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