[ECT in patients with deep brain stimulation: The first cases in the Netherlands]

Area of Science:

• Neuroscience
• Psychiatry

Background:

• Electroconvulsive therapy (ECT) is a highly effective treatment for severe depression.
• Deep brain stimulation (DBS) is increasingly used for neurological and psychiatric conditions.
• Limited research exists on the safety and efficacy of ECT in patients with DBS.

Purpose of the Study:

• To investigate the safety and efficacy of administering ECT to patients with co-existing DBS.
• To address clinical caution regarding potential risks of combining ECT and DBS.
• To expand treatment options for patients with severe depression and DBS.

Main Methods:

• Case report of two patients in the Netherlands with DBS who underwent ECT.
• DBS system was switched off during ECT administration.
• Clinical outcomes and safety parameters were monitored.

Main Results:

• ECT was administered safely and effectively in both patients with DBS.
• No adverse events related to the combination of ECT and DBS were reported.
• Successful treatment of severe depression was observed.

Conclusions:

• ECT can be safely and effectively administered to patients with DBS when the device is temporarily deactivated.
• Patients with DBS should not be excluded from ECT consideration.
• Referral to specialized centers is recommended for evaluation and management.