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Electroacupuncture Combined with Chinese Medicine Ironing Therapy for Functional Constipation

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Research on functional constipation with anxiety or depression: a bibliometric analysis.

Xiaoqin Li¹, Qiang Lei², Jiao Xie³

¹Clinical Medicine College, Jiangxi University of Chinese Medicine, Nanchang, Jiangxi, China.

Frontiers in Psychiatry

|July 3, 2025

Summary

This bibliometric study analyzes research on functional constipation (FC) linked to anxiety or depression, revealing a growing publication trend and key research areas. Future research should explore etiology, the brain-gut axis, and evidence-based treatments like fecal microbiota transplantation.

Keywords:

CiteSpace anxiety bibliometric depression functional constipation

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Area of Science:

Gastroenterology
Psychiatry
Bibliometrics

Background:

Functional constipation (FC) co-occurring with anxiety or depression is a recognized phenomenon.
Despite extensive investigation, bibliometric studies on this topic are lacking.
This study addresses the research gap by analyzing the status and trends of FC with anxiety or depression research.

Purpose of the Study:

To conduct a bibliometric analysis of research on functional constipation (FC) associated with anxiety or depression.
To identify research trends, key contributors, and emerging areas of interest.
To provide insights for future research directions in this interdisciplinary field.

Main Methods:

Bibliometric analysis of publications from 2003 to 2024.
Data sourced from the Web of Science Core Collection.
Analysis using CiteSpace and VOSviewer for publication trends, author contributions, country/institution output, and keyword co-occurrence.

Main Results:

A significant upward trend in annual publications from 2003-2024 indicates growing research interest.
A total of 427 publications were identified, predominantly original research articles (83.61%).
The United States led in publications, with Harvard University as a leading institution and Michel Bouchoucha as a prolific author.

Conclusions:

Future research should focus on the etiology and pathogenesis of FC with anxiety/depression, including the role of opioid drugs and the brain-gut axis.
Clinical research should prioritize evidence-based medicine, randomized controlled trials, and robust meta-analyses.
Novel treatment strategies such as fecal microbiota transplantation and biofeedback therapy warrant clinical exploration.