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Updated: Sep 17, 2025

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Multimodality Diagnosis of Mesenteric Ischemia
Published on: July 21, 2023
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Case Report: Giant mesenteric hemolymphangioma enveloping the ileum
Guan-Ying Yu1, Qi Liu1, Jing-Du Yan1
1Department of Gastrointestinal Surgery, Central Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China.
Frontiers in Oncology
|July 3, 2025
Summary
This case report highlights a rare hemolymphangioma in a 16-year-old male
Area of Science:
- Vascular Surgery
- Gastroenterology
- Pediatric Oncology
Background:
- Hemolymphangiomas are rare benign tumors of lymphatic and vascular origin.
- They are uncommon in the gastrointestinal tract, particularly the mesentery.
- Heterogeneous imaging can lead to misdiagnosis as malignancy.
Observation:
- A 16-year-old male presented with acute abdominal pain, vomiting, and diarrhea.
- Imaging revealed a large, heterogeneous right lower abdominal mass, initially suspected to be malignant.
- Ultrasound-guided biopsy and immunohistochemistry were crucial for diagnosis.
Findings:
- The diagnosis was confirmed as hemolymphangioma, a benign tumor.
- Surgical management involved a combined laparoscopic and open approach with en bloc resection of the tumor, ileum segment, and mesentery.
- Histopathology confirmed the tumor's lymphatic and vascular nature.
Implications:
- Hemolymphangiomas should be included in the differential diagnosis for mesenteric masses, especially in younger patients.
- Accurate diagnosis through biopsy and immunohistochemistry is essential to avoid unnecessary aggressive treatment for benign conditions.
- Successful surgical resection offers a favorable prognosis with no recurrence observed at follow-up.

