Related Experiment Video
Updated: Sep 17, 2025

Brain Imaging Investigation of the Impairing Effect of Emotion on Cognition
Published on: February 1, 2012
Delusional Distress is Associated With Emotion Dysregulation in Schizophrenia-Spectrum Disorders
Essence Leslie1, Lauren P Weittenhiller2, Ali F Sloan3
1Department of Psychiatry and Behavioral Sciences, Vanderbilt University Medical Center, 1601 23rd Ave S, Suite 3057K, Nashville, TN 37212, USA.
Background And Hypothesis:
The distressing nature of delusional beliefs is considered key to their persistence. One potential mechanism underlying delusional distress is global emotion dysregulation. Global emotion dysregulation is associated with general psychotic symptom severity, but its specific relationship to delusional distress has yet to be closely examined.
Study Design:
People with (n = 100) and without (n = 52) schizophrenia-spectrum disorders completed measures of delusional ideation (Peters Delusion Inventory; PDI-21) and global emotion dysregulation (Difficulties in Emotion Regulation Scale; DERS-16). Participants with schizophrenia also completed a measure of delusion severity (Psychotic Symptom Rating Scales; PSYRATS). Relationships between delusion severity and global emotion dysregulation were assessed with linear regression, controlling for age, sex, and group. Associations between delusional distress and aspects of emotion dysregulation were determined using stepwise linear regression.
Study Results:
Global emotion dysregulation was significantly elevated in those with schizophrenia compared to non-clinical controls, across all subscales (P < .001). Emotion dysregulation was significantly associated with delusional distress on both the PDI-21 (P < .001) and PSYRATS (P < .001). Stepwise regressions revealed a specific association between limited access to emotion regulation strategies and delusional distress on both scales (P's < .001). Delusional distress remained associated with emotion dysregulation when controlling for delusional preoccupation, and emotion dysregulation was not significantly associated with delusional conviction on either scale.
Conclusions:
Emotion dysregulation, particularly the sense that there is little one can do to regulate themselves when upset, relates to delusional distress. Interventions that increase access to more emotion regulation strategies may help decrease distress associated with delusional thinking.
More Related Videos
13:08Measurement of Fronto-limbic Activity Using an Emotional Oddball Task in Children with Familial High Risk for Schizophrenia
Published on: December 2, 2015
09:55Use of a Psychophysiological Script-driven Imagery Experiment to Study Trauma-related Dissociation in Borderline Personality Disorder
Published on: March 8, 2018
Related Concept Videos
Personality Disorders: Schizotypal and Histrionic
Schizotypal Personality Disorder: Eccentric Behavior and Social Withdrawal
Schizotypal personality disorder is marked by odd or eccentric...
Negative and Cognitive Symptoms of Schizophrenia
Negative Symptoms
Negative symptoms of schizophrenia manifest as deficits in normal emotional and behavioral functioning, profoundly impacting daily life. Individuals with schizophrenia often display a flat affect, characterized by a near-total absence of emotional expression,...
Positive Symptoms Schizophrenia: Hallucinations and Delusions
Hallucinations
Hallucinations in...
Positive Symptoms of Schizophrenia: Hallucinations and Delusions
Thought Disorders
Disorganized and unusual thought processes mark thought disorders in schizophrenia. One key feature is disorganized speech, where an individual's conversation includes...
Psychological and Sociocultural Causes of Schizophrenia
Schizophrenia