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The scale-up of microbial fermentation processes is essential in industrial biotechnology, allowing the transition from laboratory-scale experiments to commercial-scale production while aiming to maintain product yield and quality. This process requires meticulous adjustment of equipment design, process parameters, and contamination control strategies to accommodate increasing culture volumes.At the laboratory scale, cultures are typically maintained in 1 to 10-liter glass or autoclavable...
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From pixels to planning: scale-free active inference.

Karl Friston1,2, Conor Heins2, Tim Verbelen2

  • 1Queen Square Institute of Neurology, University College London, London, United Kingdom.

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Summary
This summary is machine-generated.

This study introduces renormalizing generative models (RGMs) for dynamic systems. These models learn compositionality in space and time, enabling applications from image classification to game learning.

Keywords:
Bayesian model selectionactive inferenceactive learningcompressionnetwork-physiologyrenormalization groupstructure learning

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Area of Science:

  • Artificial Intelligence
  • Machine Learning
  • Computational Neuroscience

Background:

  • Generative modeling is crucial for understanding and predicting dynamic systems.
  • Partially observed Markov decision processes (POMDPs) are a standard framework but can be limited in modeling complex temporal dependencies.
  • Existing models often struggle with compositionality across space and time.

Purpose of the Study:

  • To introduce a novel discrete state-space model for generative modeling, generalizing POMDPs.
  • To develop renormalizing generative models (RGMs) capable of learning compositionality over space and time.
  • To demonstrate the versatility of RGMs through diverse applications in learning and inference.

Main Methods:

  • Developed a discrete state-space model that incorporates paths as latent variables.
  • Utilized deep or hierarchical forms inspired by the renormalization group.
  • Applied variational principles for automatic discovery, learning, and deployment of RGMs.

Main Results:

  • RGMs are shown to be discrete homologs of deep convolutional neural networks and continuous state-space models.
  • The models exhibit scale-invariance and learn compositionality over space and time, modeling paths and orbits.
  • Successful applications demonstrated in image classification, movie and music generation, and learning Atari-like games.

Conclusions:

  • Renormalizing generative models offer a powerful new framework for generative modeling in dynamic settings.
  • RGMs provide a principled way to learn hierarchical, compositional representations from data.
  • The demonstrated applications highlight the broad applicability and effectiveness of RGMs across various domains.