A Case of Primary Urethral Malignant Melanoma With Persistent Bleeding and Severe Anemia

Primary malignant melanomas of the urethra are extremely rare. The initial symptoms typically include hematuria or genital bleeding. This report describes a case of a massive primary urethral malignant melanoma with persistent bleeding.

An 84-year-old woman presented with bleeding and pain from a vulvar mass and severe anemia. She presented with a fist-sized dark-brown multifocal mass extending from the urethra, with persistent bleeding and anemia in the same area. After blood transfusion, tumor resection was performed. Histopathological analysis confirmed the presence of primary malignant urethral melanoma.

Urethral malignant melanoma is a rare and aggressive disease that often presents with symptoms that mimic benign conditions. Despite poor prognosis, early surgical resection with adequate margins is crucial. This case highlights the importance of considering malignant melanomas in the differential diagnosis of atypical urethral masses, particularly in patients with persistent bleeding.