Related Experiment Video
Updated: Sep 17, 2025
04:57
Establishing a Competing Risk Regression Nomogram Model for Survival Data
Published on: October 23, 2020
10.3K
Understanding global variation in breast cancer mortality
Marwa M A Elbasheer1, David Dodwell2,3, Toral Gathani1,3
1Cancer Epidemiology Unit, Nuffield Department of Population Health, University of Oxford, Oxford, OX3 7LF, United Kingdom.
The British Journal of Radiology
|July 3, 2025
Summary
Breast cancer poses a global health challenge, with incidence and mortality rates varying significantly worldwide. Conflict, as seen in Sudan, severely impacts cancer care and worsens outcomes, especially in less developed regions.
Area of Science:
- Oncology
- Global Health
- Epidemiology
Background:
- Breast cancer is the most common cancer and leading cause of cancer mortality among women globally.
- Significant disparities exist in breast cancer incidence and mortality rates between developed and less developed countries.
- Projected increases in breast cancer cases and deaths by 2050 highlight the growing global burden, particularly in less developed regions.
Purpose of the Study:
- To discuss the global variations in breast cancer mortality rates.
- To examine the impact of conflict on cancer care using a case study.
- To highlight challenges in addressing breast cancer in less developed countries.
Main Methods:
- Review of global breast cancer incidence and mortality data.
- Analysis of trends in developed versus less developed countries.
- Case study analysis of breast cancer care in Sudan.
Main Results:
- Developed countries have seen reductions in breast cancer mortality over the past 40 years.
- Less developed countries face challenges in reducing breast cancer mortality.
- Conflict situations, exemplified by Sudan, have a devastating impact on cancer care delivery and outcomes.
Conclusions:
- Global breast cancer mortality rates exhibit significant variation, with higher rates in less developed regions.
- Addressing disparities in breast cancer care and outcomes requires targeted interventions, especially in low-resource settings.
- Conflict exacerbates existing challenges in cancer care, necessitating urgent attention to maintain essential health services.
More Related Videos
07:47Author Spotlight: Unveiling Transmembrane Protein Family-Related Markers in Gastric Cancer and Implications for Targeted Therapies
Published on: September 15, 2023
1.7K
07:41Performing Data Mining And Integrative Analysis Of Biomarker in Breast Cancer Using Multiple Publicly Accessible Databases
Published on: May 17, 2019
9.1K
Related Concept Videos
01:21Cancer Survival Analysis
457
Cancer survival analysis focuses on quantifying and interpreting the time from a key starting point, such as diagnosis or the initiation of treatment, to a specific endpoint, such as remission or death. This analysis provides critical insights into treatment effectiveness and factors that influence patient outcomes, helping to shape clinical decisions and guide prognostic evaluations. A cornerstone of oncology research, survival analysis tackles the challenges of skewed, non-normally...
457
01:20Comparing the Survival Analysis of Two or More Groups
297
Survival analysis is a cornerstone of medical research, used to evaluate the time until an event of interest occurs, such as death, disease recurrence, or recovery. Unlike standard statistical methods, survival analysis is particularly adept at handling censored data—instances where the event has not occurred for some participants by the end of the study or remains unobserved. To address these unique challenges, specialized techniques like the Kaplan-Meier estimator, log-rank test, and...
297
02:07Tumor Progression
6.5K
Tumor progression is a phenomenon where the pre-formed tumor acquires successive mutations to become clinically more aggressive and malignant. In the 1950s, Foulds first described the stepwise progression of cancer cells through successive stages.
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
Colon cancer is one of the best-documented examples of tumor progression. Early mutation in the APC gene in colon cells causes a small growth on the colon wall called a polyp. With time, this polyp grows into a benign, pre-cancerous tumor. Further...
6.5K
01:29Bias in Epidemiological Studies
697
Biases can arise at various stages of research, from study design and data collection to analysis and interpretation. Recognizing and addressing these biases is essential to ensure the validity and reliability of epidemiological findings.Broadly speaking, biases in epidemiology fall into three main categories: selection bias, information bias, and confounding. A more detailed description of possible biases is:
697
01:12Relative Risk
356
Relative risk (RR) is a statistical measure commonly used in epidemiology to compare the likelihood of a particular event occurring between two groups. This metric is important for evaluating the relationship between exposure to a specific risk factor and the probability of a particular outcome. It plays a crucial role in medical research, public health studies, and risk assessment. Relative risk quantifies how much more (or less) likely an event is to occur in an exposed group compared to an...
356
02:18Cancer
49.7K
Cancers arise due to mutations in genes involved in the regulation of cell division, which leads to unrestricted cell proliferation. Modern science and medicine have made great strides in the understanding and treatment of cancer, including eradicating cancer in some patients. However, there is still no cure for cancer. This is largely due to the fact that cancer is a large group of many diseases.
49.7K