Emotional changes of patients undergoing maintenance hemodialysis during the COVID-19 lockdown

Qianyun Zhao1, Yuyu Zhu1, Junyi Jiang1

  • 1Institute of Nephrology and Inflammatory Immune Diseases, the Second Affiliated Hospital of Anhui Medical University, Hefei, China.

Annals of Medicine
|July 3, 2025
PubMed

Insights

The COVID-19 lockdown significantly increased anxiety, anger, loneliness, and depression in hemodialysis patients. This highlights the need for mental health support during public health crises for this vulnerable population.

Area of Science:

  • Psychiatry
  • Nephrology
  • Public Health

Background:

  • Maintenance hemodialysis patients face unique challenges, potentially exacerbated by external stressors.
  • The COVID-19 pandemic and associated lockdowns presented unprecedented public health challenges.

Purpose of the Study:

  • To investigate the impact of the COVID-19 lockdown on negative emotions in patients undergoing maintenance hemodialysis.
  • To assess changes in anxiety, anger, loneliness, and depression during the lockdown period.

Main Methods:

  • A cross-sectional survey was conducted with 174 maintenance hemodialysis patients.
  • The Medical Staff Stress and Negative Emotions Scale (MSSNS) was used to measure emotional states before and during the lockdown.

Main Results:

  • Patients reported significantly higher scores for anxiety, anger, loneliness, and depression during the lockdown compared to the pre-lockdown period (p < 0.001).
  • All collected questionnaires (n=174) were valid, indicating robust data collection.

Conclusions:

  • The COVID-19 lockdown period was associated with a significant increase in negative emotions among hemodialysis patients.
  • There is a critical need to prioritize and support the mental well-being of hemodialysis patients during public health emergencies.
Abstract

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