Related Experiment Video

Updated: May 7, 2026

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations
14:58

Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

Published on: October 20, 2017

9.8K

Brainstem cavernous malformations in pediatrics: case report and literature review

Antonio Heredia-Gutiérrez1,2, María E Carbarín-Carbarín3

  • 1Servicio de Neurocirugía Pediátrica, Hospital para el Niño Poblano, San Andrés Cholula.

Cirugia Y Cirujanos
|July 3, 2025
PubMed

Insights

Cavernous malformations in the brainstem are rare in children. Surgical resection of a symptomatic brainstem cavernous malformation in a pediatric patient led to complete symptom resolution, highlighting surgery as a viable treatment.

Area of Science:

  • Neurology
  • Neurosurgery
  • Pediatrics

Background:

  • Cavernous malformations (CMs) affect 0.4%-0.8% of the population.
  • Symptoms include seizures, headaches, and neurological deficits.
  • Brainstem CMs in pediatric patients are infrequent.

Purpose of the Study:

  • To report a case of a pediatric patient with a brainstem cavernous malformation.
  • To discuss the management and outcomes of brainstem CMs in children.

Main Methods:

  • Case presentation of a 10-year-old girl with neurological deficits.
  • Diagnostic imaging using magnetic resonance imaging (MRI) of the brain.
  • Surgical resection of the pontobulbar lesion.

Main Results:

  • The patient presented with headache, right hemiparesis, ataxia, and cranial nerve deficits (VI, VII, IX, X).
  • MRI revealed a left pontobulbar lesion consistent with a cavernous malformation.
  • One year post-surgery, the patient experienced complete resolution of symptoms.

Conclusions:

  • Surgical resection is recommended for symptomatic brainstem cavernous malformations in pediatric patients.
  • Neurological surveillance is appropriate for asymptomatic lesions.
  • This case underscores the efficacy of surgical intervention for pediatric brainstem CMs.

Keywords:
Brain cavernous malformationBrainstemMalformación cavernomatosa cerebralNeurocirugíaNeurosurgeryPediatricsPediatríaTallo cerebral

More Related Videos

Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model05:12

Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model

Published on: September 4, 2017

11.0K
Author Spotlight: A Single-Entry Point Endoscopic Intraventricular Approach for Third Ventriculostomy and Pineal Biopsy03:13

Author Spotlight: A Single-Entry Point Endoscopic Intraventricular Approach for Third Ventriculostomy and Pineal Biopsy

Published on: June 28, 2024

815

Related Concept Videos

Brain Abscess l: Introduction01:26

Brain Abscess l: Introduction

A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
Cerebral Edema ll: Pathophysiology01:22

Cerebral Edema ll: Pathophysiology

Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this barrier loses...