Related Experiment Video
Updated: Sep 17, 2025

Quantitative PCR-based Assay to Measure Sonic Hedgehog Signaling in Cellular Model of Ciliogenesis
Published on: January 31, 2025
Hedgehog pathway, cell cycle, and primary cilium
1Institute of Veterinary Immunology and Engineering, Jiangsu Academy of Agricultural Sciences, Nanjing, Jiangsu, China. zhuangtenghan@foxmail.com.
Abstract:
The Hedgehog (Hh) pathway was initially identified as essential for development and tumorigenesis. In addition to its well-established and indispensable roles within the primary cilium, some components of this pathway have demonstrated more general functions in cell cycle progression. Therefore, this review aims to summarize recent advancements regarding the crosstalk among the Hh pathway, the primary cilium, and the cell cycle, while also highlighting potential issues that may arise in future research.
Related Concept Videos
Hedgehog Signaling Pathway
Microtubules in Signaling
Cell Polarization by Rho Proteins
The Cell Cycle Control System
Cyclins and cyclin-dependent kinases (Cdks) are the primary cell cycle regulators and...
Microtubules in Cell Motility
Positive Regulator Molecules

