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Author Spotlight: Unveiling Prognostic Indicators in Heart Failure - The Role of Phase Angle and Bioelectrical Impedance Analysis
Published on: June 30, 2023
Correlation between Visceral Adiposity Index (VAI) and Congestive Heart Failure (CHF) in patients with hypertension:
Ziyin Fan1, Li Yang1, Jia Song1
1Department of Cardiology, Zhuzhou Central Hospital, No. 116, South Changjiang Road, Tianyuan District, Zhuzhou, Hunan, 412000, China.
Insights
Visceral adiposity index (VAI) is linked to increased congestive heart failure (CHF) risk in hypertension patients. This study confirms VAI as an effective tool for assessing CHF risk in this population.
Area of Science:
- Cardiology
- Metabolic Syndrome
- Public Health
Background:
- Hypertension is a global health concern, closely associated with congestive heart failure (CHF).
- Visceral adiposity index (VAI) is an emerging marker for visceral fat accumulation.
Purpose of the Study:
- To investigate the correlation between visceral adiposity index (VAI) and the risk of congestive heart failure (CHF) in individuals with hypertension.
- To evaluate the effectiveness of VAI in predicting CHF risk within the hypertensive population.
Main Methods:
- Utilized data from the National Health and Nutrition Examination Survey (NHANES) from 2001 to 2018.
- Employed weighted logistic regression, propensity score matching (PSM), and restricted cubic spline (RCS) analysis.
- Conducted subgroup analyses based on sex, age, race, and comorbidities.
Main Results:
- A significant positive correlation was observed between VAI and CHF risk in multivariable logistic regression (OR=1.15, 95% CI: 1.04, 1.29).
- This association remained significant after PSM (OR=1.24, 95% CI: 1.06, 1.45) and exclusion of cardiovascular disease patients.
- RCS analysis revealed a significant linear relationship between VAI and CHF risk (P=0.018).
Conclusions:
- Visceral adiposity index (VAI) is a significant predictor of congestive heart failure (CHF) risk in patients with hypertension.
- VAI serves as an effective tool for risk stratification of CHF in hypertensive individuals.
Background:
Hypertension is one of the most prevalent chronic diseases globally and is closely related to congestive heart failure (CHF). In this study, we explored the correlation between the risk of CHF in individuals with hypertension and the visceral adiposity index (VAI).
Method:
This study used data from the National Health and Nutrition Examination Survey (NHANES) spanning from 2001 to 2018. A weighted logistic regression model was used to assess the relationship between VAI and CHF. To further explore their relationship, propensity score matching (PSM), confounder adjustment methods, restricted cubic spline (RCS) analysis for nonlinearity, and subgroup analyses by sex, age, and race were also performed.
Results:
A total of 3,613 patients were included in the study. Multivariable logistic regression analysis showed that in the fully adjusted model, there was a significant positive correlation between VAI and CHF (OR = 1.15, 95% CI: 1.04, 1.29); this association remained significant after PSM matching (OR = 1.24, 95% CI: 1.06, 1.45); and the association was still significant after excluding patients with CHD, MI, or stroke (OR = 1.15, 95% CI: 1.04, 1.29). RCS results indicated a significant linear relationship between VAI and the risk of CHF (P-overall = 0.018, P-non-linear = 0.964). Subgroup analysis revealed a significant positive correlation between VAI and CHF in males, individuals under 60 years of age, those with educational attainment below high school, patients with diabetes, drinkers, non-smokers, non-CHD patients, those with AP, and non-stroke patients.
Conclusions:
This study demonstrates that VAI is effective for CHF risk assessment in hypertensive patients.
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