Related Experiment Video
Updated: Sep 17, 2025
Development of Amelogenin-chitosan Hydrogel for In Vitro Enamel Regrowth with a Dense Interface
Published on: July 10, 2014
Enamel matrix derivative and root coverage: A literature review
Edgar Daniel Vargas Quiroga1, Brenda Carolina Pattigno Forero2, Gloria Estefanía Amaya Chica1
1Department of Oral & Maxillofacial Surgery and Periodontology, Ribeirao Preto Dental School (FORP/USP), University of Sao Paulo. Ribeirao Preto, Sao Paulo. Brazil. edgardanielvargasquiroga@gmail.com, g.amayachica@gmail.com, marilia.bianchini.reis@gmail.com Universidade de São Paulo Department of Oral & Maxillofacial Surgery and Periodontology Ribeirao Preto Dental School (FORP/USP) University of Sao Paulo Ribeirao PretoSao Paulo Brazil edgardanielvargasquiroga@gmail.com g.amayachica@gmail.com marilia.bianchini.reis@gmail.com.
Introduction:
: The use of enamel matrix derivative proteins, also known as Emdogain®, has revolutionized clinical practice in dentistry since the 90s. This biomaterial has demonstrated to promote periodontal tissues regeneration lost due to periodontal disease which persists as a public health problem, emerging as an effective alternative in treatments such as non-surgical periodontal therapy, treatment of furcation lesions, intraosseous defects, and more recently, its use has become especially popular in root coverage surgeries.
Objective:
: Evaluate studies in reference to the use of enamel-derived matrix proteins in periodontal treatments, to offer a comprehensive and up-to-date vision of its impact and effectiveness.
Materials And Methods:
: Systematic review was conducted about randomized clinical trials (RCTs) published between 2019 and 2024, using databases PubMed and Scopus, considering Clinical measurements performed in the studies.
Results:
The analyzed studies compared different surgical techniques for the treatment of gingival recessions, focusing on the percentage of root coverage (RC), clinical attachment gain (CAL), increase in gingival thickness (KTW), long-term stability, and postoperative pain (VAS).
Conclusion:
EMD significantly contributes to improvement of periodontal regeneration and long-term outcomes of root coverage surgeries, results obtained show a lot of variability. Randomized controlled trials are necessary to evaluate efficacy in different clinical contexts.
More Related Videos
07:42Quasistatic Mechanical Testing for Computer-Aided Design and Manufacturing Occlusal Veneers Cemented to Milled Dentin Analog Material
Published on: December 20, 2024
06:16Author Spotlight: Establishing an Accurate Microhardness Testing Protocol for Craniofacial Tissues
Published on: April 26, 2024
Related Concept Videos
01:21Tooth Anatomy
The Crown, Neck, and Root
The visible part of the tooth is referred to as the crown. It's covered by enamel, the hardest substance in the human body. The crown is uniquely shaped for each type of tooth, allowing for different functions such as cutting, tearing, or...
01:15Teeth
In the bud stage, the tooth germ (an aggregation of cells) starts to form in the developing jawbone. During the cap stage, the tooth germ differentiates into enamel organ, dental papilla, and dental sac, which will later develop into the tooth's enamel, dentin...