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Canadian impact of CLSI aminoglycoside breakpoint changes for selected gram-negative bacteria
Ellen Germaine Avery1, Taylor Laughlin2, Kevin Brown3
1Department of Laboratory Medicine & Pathobiology, University of Toronto, Toronto, ON, Canada.
Abstract:
We evaluated the impact of recent revisions to the Clinical and Laboratory Standards Institute (CLSI) aminoglycoside breakpoints on susceptibility within Enterobacterales and Pseudomonas aeruginosa at a Canadian academic hospital. While the aminoglycoside breakpoint changes minimally affected overall susceptibility, the impact of these changes was notable within beta-lactamase producing Enterobacterales.
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