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Updated: Sep 16, 2025

Antimicrobial Characterization of Advanced Materials for Bioengineering Applications
Published on: August 4, 2018
Recent advances in metal-based antimicrobial coatings
Patrícia Pereira-Silva1, Joel Borges2, Paula Sampaio3
1Centre of Molecular and Environmental Biology (CBMA), Department of Biology, University of Minho, 4710-057 Braga, Portugal; Physics Center of Minho and Porto Universities (CF-UM-UP), University of Minho, Campus de Azurém, 4800-058 Guimarães, Portugal.
Copper-based antimicrobial coatings show superior performance, emerging as a promising alternative to silver. Further research is needed to understand mechanisms and real-world effectiveness.
Area of Science:
- Materials Science
- Microbiology
- Surface Chemistry
Background:
- Metal-based antimicrobial coatings are crucial for controlling microbial contamination in diverse industries.
- Recent advancements (2021-2023) focus on novel metal and metal compound coatings.
- Silver remains dominant, but copper shows significant antimicrobial potential.
Purpose of the Study:
- To systematically review recent advancements in metal-based antimicrobial coatings.
- To comparatively analyze antimicrobial performance (R) of various metal coatings.
- To identify technological progress and knowledge gaps for practical implementation.
Main Methods:
- Systematic literature review of 43 studies published between 2021 and 2023.
- Analysis of antimicrobial performance data from selected publications.
- Inclusion of insights from top ten patents and eight commercial products.
Main Results:
- Copper-based coatings demonstrate the highest antimicrobial performance, surpassing silver.
- Silver-based coatings are the most researched and commercially available.
- Most studies focus on bacterial inactivation, with limited data on fungi and viruses.
Conclusions:
- Copper emerges as a strong alternative to silver for antimicrobial coatings.
- The molecular mechanisms of action require further investigation.
- Real-world effectiveness assessments are limited, highlighting a critical research gap.
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