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Dengue and hepatic failure.

M E Alvarez, C H Ramírez-Ronda

The American Journal of Medicine

|November 1, 1985

Summary

This summary is machine-generated.

Secondary dengue infection can cause severe hepatitis, encephalopathy, and coagulopathy, even in adults. This case highlights the importance of considering dengue in unexplained illnesses in endemic areas.

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Area of Science:

Infectious Diseases
Neurology
Hepatology

Background:

Dengue hemorrhagic fever/dengue shock syndrome is a severe dengue manifestation.
Primarily seen in tropical West Pacific and Southeast Asia.
Often linked to secondary dengue infections in children.

Observation:

A 51-year-old man with secondary dengue infection presented with severe hepatitis.
Clinical manifestations included encephalopathy and cranial nerve palsy.
Microangiopathic coagulopathy was also noted.

Findings:

The patient experienced severe hepatitis, encephalopathy, cranial nerve palsy, and coagulopathy.
Despite the severity, the patient had a favorable outcome.
This case demonstrates dengue's potential to cause severe, multi-systemic illness in adults.

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Implications:

Suggests increased surveillance for secondary dengue in the Western Hemisphere.
Recommends considering dengue in febrile illnesses with hepatitis, encephalopathy, or coagulopathy.
Highlights the role of Aedes aegypti mosquito presence in disease transmission.