Related Experiment Video
Updated: Sep 16, 2025

Prehospital Thrombolysis: A Manual from Berlin
Published on: November 26, 2013
Rural Outreach: Door to Thrombolytics
Sarah A Herrera1, Janet L Tuttle1
1Intermountain Health, St. Mary's Regional Hospital, Grand Junction, Colorado, USA.
A new transfer protocol significantly reduced treatment times for ST-segment elevation myocardial infarction (STEMI) patients transferred from rural facilities. Door-to-thrombolytic administration time decreased by 71%, improving care for critical cardiac events.
Area of Science:
- Cardiology
- Emergency Medicine
- Healthcare Systems
Background:
- St. Mary's Regional Hospital (SMRH) serves a vast rural area, with 45% of ST-segment elevation myocardial infarction (STEMI) cases originating from transfers.
- Facility A, a rural Colorado hospital, relies on SMRH for advanced care and uses thrombolytics as first-line STEMI treatment due to limited cath lab access.
Observation:
- Facility A experienced a prolonged average door-to-thrombolytic administration time of 79.5 minutes for STEMI patients.
- This extended time for STEMI treatment at Facility A, a major transfer source for SMRH, prompted an investigation.
Findings:
- SMRH cardiology team developed and implemented a new transfer protocol to streamline STEMI treatment processes.
- Following protocol implementation, door-to-thrombolytic administration times at Facility A were reduced by 71% within 18 months.
Implications:
- The new protocol significantly decreased STEMI treatment delays, achieving a 2024 year-end average of 23 minutes.
- This initiative demonstrates the effectiveness of standardized transfer protocols in improving time-sensitive cardiac care for rural populations.
Related Concept Videos
Venous Thrombosis III: Interprofessional Care
Venous Thrombosis IV: Nursing Management
Peripheral Artery Disease III: Interprofessional Care
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care
Clot Retraction and Fibrinolysis
Atherosclerosis IV: Nursing Management

