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Treating a Metastatic Pericardial Tumor.
Leslie A Ynalvez1, Cezar A Iliescu1, Ihab R Hamzeh1
1Department of Cardiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
JACC. Case Reports
|July 4, 2025
Summary
Metastatic adenocarcinoma rarely involves the pericardium. A combination of pericardiocentesis with drain placement and systemic chemotherapy effectively treated effusive-constrictive pericarditis (ECP) in a gastrointestinal cancer patient.
Area of Science:
- Oncology
- Cardiology
- Gastroenterology
Background:
- Pericardial metastasis from adenocarcinoma is uncommon.
- Treatment for malignant pericardial effusion has varied historically.
Observation:
- A patient with gastrointestinal adenocarcinoma developed pericardial metastasis presenting as effusive-constrictive pericarditis (ECP).
- The patient underwent pericardiocentesis with drain placement followed by systemic chemotherapy.
Findings:
- This management approach led to the resolution of pericardial disease.
- The patient experienced an improved quality of life.
Implications:
- Pericardiocentesis with temporary drain placement and subsequent systemic chemotherapy is a viable strategy for malignant ECP.
- This approach aims to reduce fluid reaccumulation and tumor infiltration while minimizing treatment-related side effects.
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