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Understanding the gap between expectations and reality in decentralized clinical trials
Yale Jiang1, Ye Leng1, Qing Wu1
1Clinical Trial Center, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Decentralized clinical trials (DCTs) show promise but are not yet mainstream. This study analyzes their development, identifies barriers, and suggests strategies for wider adoption in clinical research.
Area of Science:
- Clinical research methodology
- Health informatics
Background:
- Decentralized clinical trials (DCTs) have garnered significant attention in recent years.
- Despite regulatory and industry acceptance, widespread adoption as a standard clinical trial paradigm remains limited.
Purpose of the Study:
- To investigate the evolutionary trends and current developmental stage of DCTs.
- To identify the underlying factors influencing the adoption rate of DCTs.
- To propose actionable solutions for the sustainable implementation of DCTs.
Main Methods:
- Analysis of DCT evolutional trends.
- Identification of barriers to DCT adoption.
- Development of strategies for sustainable DCT implementation.
Main Results:
- DCTs are still in an emerging phase, not yet at their peak adoption.
- Specific reasons for the current development stage have been identified.
Conclusions:
- The full potential of DCTs has not yet been realized.
- Proactive strategies are necessary to overcome existing challenges and promote sustainable DCT implementation.
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