Knowledge mapping of micro/nanomotors in cancer treatment: a bibliometric analysis (2006-2025)

Ying Song1, Kai Zhao2, Yan Yang1

  • 1Department of Pharmacy, Shengli Oilfield Central Hospital, Dongying, 257034, Shandong, China.

Discover Oncology
|July 4, 2025
PubMed
Abstract

Insights

This bibliometric analysis reveals China

Area of Science:

  • Nanomedicine
  • Biomedical Engineering
  • Cancer Therapy

Background:

  • Malignant tumors present challenges due to heterogeneity and limitations of traditional therapies.
  • Nanomedicine, especially micro/nanomotors, offers advanced tumor penetration capabilities.
  • Systematic bibliometric insights into nanomotor research for cancer are lacking.

Purpose of the Study:

  • To conduct a bibliometric analysis of micro/nanomotor research in nanomedicine.
  • To map the research landscape, identify key contributors, and analyze trends.
  • To provide strategic guidance for future research and clinical translation.

Main Methods:

  • Bibliometric analysis of 10,609 articles published between 2006 and 2025.
  • Data sourced from the Web of Science Core Collection (WoSCC).
  • Analysis performed using CiteSpace, VOSviewer, and bibliometric methods.

Main Results:

  • China leads global research output with 380 publications (62.4%).
  • The Chinese Academy of Sciences and ACS NANO are leading institutions and journals, respectively.
  • The keyword 'penetration' shows a strong citation burst (2021-2025), indicating progress in overcoming tumor barriers.

Conclusions:

  • China dominates nanomotor research for cancer therapy.
  • Research is rapidly evolving towards intelligent actuation and immunotherapy integration.
  • Tumor penetration remains a pivotal research frontier for nanomedicine.

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