Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Mitral Valve Prolapse I: Introduction

Mitral Valve Prolapse I: Introduction

IntroductionThe mitral valve, one of the heart's four valves, regulates blood flow. These valves have flaps that open and close to direct blood properly through the heart and body. During each heartbeat, the flaps open for blood to pass through and seal shut to prevent backflow. Specifically, the mitral valve opens to allow blood flow from the heart's upper left chamber to the lower left chamber. It then closes securely as the lower left chamber contracts to pump blood to the body, preventing...

Mitral Stenosis III: Medical Management

Mitral Stenosis III: Medical Management

Mitral stenosis, a condition marked by the narrowing of the mitral valve, necessitates an integrated approach for effective management. This approach includes preventative measures, medical therapy, and surgical interventions to reduce symptoms and prevent complications.PreventionPrevention of mitral stenosis primarily focuses on reducing the incidence of bacterial infections, particularly streptococcal infections, which can lead to rheumatic fever and subsequent valvular damage. Timely...

Mitral Stenosis I: Introduction

Mitral Stenosis I: Introduction

Mitral Valve Stenosis (MVS) is a heart condition where the mitral valve narrows, impeding blood circulation from the left atrium to the left ventricle. The etiology and pathophysiology of this condition are multifaceted, leading to a cascade of cardiovascular complications.Causes of Mitral Valve StenosisRheumatic Heart Disease: It is the main cause of mitral valve stenosis, particularly in developing nations. This condition arises from rheumatic fever, an inflammatory illness resulting from...

Mitral Stenosis IV: Nursing Management

Mitral Stenosis IV: Nursing Management

A comprehensive nursing assessment is essential for patients with valvular heart disease, which involves any dysfunction of the heart valves that could impact blood flow and overall heart function.Subjective Data Collection:Chief Complaint and Present Illness: Start with the patient's primary concerns, focusing on the onset, duration, and progression of cardiac symptoms such as dyspnea, fatigue, chest pain, and palpitations.Past Medical History: Collect detailed information on any previous...

Mitral Regurgitation III: Medical Management

Mitral Regurgitation III: Medical Management

Mitral regurgitation (MR) is characterized by retrograde blood circulation from the left ventricle into the left atrium due to inadequate mitral valve closure. The severity of the condition, symptoms, and underlying cause determine treatment strategies.Monitoring and Pharmacological TreatmentPatients with mild to moderate MR typically do not need immediate intervention but regular monitoring to assess progression and guide treatment. Patients with mild MR should have an echocardiogram every 3-5...

Mitral Valve Prolapse II: Assessment and Management

Mitral Valve Prolapse II: Assessment and Management

IntroductionA range of clinical features characterizes Mitral Valve Prolapse (MVP), but it is important to note that many individuals with MVP are asymptomatic and may remain so throughout their lives. For those who do exhibit symptoms, the following are the key clinical features:Palpitations: This is a common symptom where individuals feel an irregular or rapid heartbeat. Palpitations in MVP are often due to arrhythmias such as premature ventricular contractions or supraventricular...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Mind the missed-fibrinolysis gap.

European heart journal. Quality of care & clinical outcomes·2026

Same author

Comparative 30-day echocardiographic outcomes of Myval vs. Sapien and Evolut THVs: insights from LANDMARK trial.

European heart journal. Cardiovascular Imaging·2025

Same author

Ramipril After Transcatheter Aortic Valve Implantation in Patients Without Reduced Ejection Fraction: The RASTAVI Randomized Clinical Trial.

Journal of the American Heart Association·2024

Same author

A streamlined pathway for transcatheter aortic valve implantation: the BENCHMARK study.

European heart journal·2024

Same author

Associations of Alcohol Consumption With Left Atrial Morphology and Function in a Population at High Cardiovascular Risk.

Journal of the American Heart Association·2024

Same author

Correspondence on 'Echocardiographic estimation of pulmonary pressure in patients with severe tricuspid regurgitation' by Lemarchand <i>et al</i>.

Heart (British Cardiac Society)·2024

Search research articles

Related Experiment Video

Updated: Sep 16, 2025

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair

Published on: October 16, 2021

Intermittent mitral prosthetic dysfunction. what interferes the valve closure?

Pere Pericas^1,2, Ronald Morales Murillo³, Marta Noris Mora^3,4

¹Cardiology Department, Hospital Universitari Son Espases, Carretera de Valldemossa 79, Palma, Balearic Islands, 07120, Spain. pedroa.pericas@ssib.es.

Journal of Cardiothoracic Surgery

|July 4, 2025

Summary

This summary is machine-generated.

A rare case of prosthetic mitral valve dysfunction was caused by spontaneous papillary muscle rupture, leading to intermittent mitral regurgitation. Surgical intervention successfully corrected the issue, highlighting the importance of echocardiography and exploration.

Keywords:

Intermittent mitral regurgitation Papillary muscle rupture Prosthetic valve dysfunction Subvalvular apparatus entrapment

More Related Videos

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat

Published on: May 19, 2020

Related Experiment Videos

Last Updated: Sep 16, 2025

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair

A Simplified Stepwise Approach to Echo Guidance during Percutaneous Mitral Valve Repair

Published on: October 16, 2021

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Fully Endoscopic Mitral Valve Repair with Percutaneous Cannulation of Groin Vessels

Published on: May 26, 2023

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat

An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat

Published on: May 19, 2020

Area of Science:

Cardiology
Cardiac Surgery
Echocardiography

Background:

Prosthetic valve dysfunction can rarely occur due to subvalvular apparatus entrapment, especially as a delayed complication.
Spontaneous papillary muscle rupture without an ischemic event is uncommon.
The simultaneous occurrence of these conditions is exceptional.

Observation:

A 72-year-old woman with a mechanical mitral valve prosthesis developed severe mitral regurgitation two years post-surgery.
Transesophageal echocardiography revealed a ventricular mass obstructing the prosthesis closure.
Differential diagnoses included subvalvular remnants, vegetation, thrombus, or pannus.

Findings:

Surgical exploration identified spontaneous rupture of the anterolateral papillary muscle as the cause of prosthetic valve dysfunction.
Excision of the ruptured subvalvular apparatus led to a favorable outcome.

Implications:

This case highlights a rare etiology of late prosthetic mitral valve dysfunction.
Transesophageal echocardiography is vital for diagnosing the mechanism.
Surgical exploration is definitive for diagnosis and treatment.