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Use of a Percutaneous Ventricular Assist Device/Left Atrium to Femoral Artery Bypass System for Cardiogenic Shock
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Left Ventricular Assist Device, Implantable Cardioverter Defibrillator, and Radiation Therapy: A Technical Report,

Alexander Bennassi1, Tony Truong2, Nhu Hanh To1

  • 1Department of Radiation Oncology And Henri Mondor Breast Center, Hôpital Henri Mondor, Créteil, France; Institut Mondor de Recherche Biomédicale (IMRB), INSERM U955, i-Biot and University of Paris East Créteil (UPEC), France.

Practical Radiation Oncology
|July 5, 2025
PubMed

Insights

Managing patients with both implantable cardioverter defibrillators (ICDs) and left ventricular assist devices (LVADs) during radiation therapy (RT) requires careful planning. This case report details considerations for safe RT delivery in patients with advanced cardiac devices.

Area of Science:

  • Cardiology
  • Radiation Oncology
  • Medical Physics

Background:

  • Cardiology advancements have improved survival for patients with severe heart conditions requiring implantable cardioverter defibrillators (ICDs) and left ventricular assist devices (LVADs).
  • Radiation therapy (RT) is a critical cancer treatment, but its delivery poses challenges for patients with cardiac devices.
  • Managing patients with both ICDs and LVADs during RT requires addressing potential device malfunctions and radiation interactions.

Purpose of the Study:

  • To present a case of a patient with both a triple-chamber ICD and an electronically equipped LVAD undergoing RT.
  • To explore dosimetric considerations and device interactions during RT for patients with advanced cardiac devices.
  • To provide recommendations for the safe and effective integration of RT in this patient population.

Main Methods:

  • Case report of a patient with a triple-chamber ICD and an electronically equipped LVAD undergoing RT.
  • Analysis of dosimetric considerations and potential device interactions.
  • Development of adapted simulations to minimize risks associated with RT delivery.

Main Results:

  • The study highlights the unique challenges in managing patients with combined ICD and LVAD devices during RT.
  • Identified specific risks related to radiation exposure and device function.
  • Demonstrated the necessity of adapted simulations and careful planning for RT delivery.

Conclusions:

  • Safe and effective RT delivery is achievable in patients with advanced cardiac devices like ICDs and LVADs.
  • Careful consideration of dosimetric factors, device interactions, and adapted simulations is crucial.
  • This work bridges a knowledge gap, offering recommendations for managing these complex cases.

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