Related Experiment Video

Updated: Sep 26, 2026

Isolation and Cannulation of Cerebral Parenchymal Arterioles
09:49

Isolation and Cannulation of Cerebral Parenchymal Arterioles

Published on: May 23, 2016

Cerebral arteriovenous malformations in children

T Kurokawa, A Matsuzaki, K Hasuo

    Brain & Development
    |January 1, 1985
    PubMed

    Insights

    Pediatric arteriovenous malformations (AVM) present differently based on rupture status. Ruptured AVMs (RAM) typically cause sudden intracranial hemorrhage, while unruptured AVMs (URAM) show chronic, milder symptoms.

    Area of Science:

    • Pediatric Neurology
    • Neurosurgery
    • Radiology

    Background:

    • Arteriovenous malformations (AVM) are complex vascular anomalies.
    • Understanding clinical differences between ruptured and unruptured AVMs in children is crucial for diagnosis and management.

    Purpose of the Study:

    • To compare the clinical features of ruptured arteriovenous malformations (RAM) and unruptured arteriovenous malformations (URAM) in pediatric patients.

    Main Methods:

    • Retrospective case series comparing clinical presentations, age at onset, and imaging findings.
    • Analysis of six children with RAM and three with URAM.

    Main Results:

    • Age at onset: Neonatal to 8 years for URAM vs. 10 to 12 years for RAM.
    • RAM presented with sudden intracranial hemorrhage, whereas URAM showed chronic symptoms like developmental delay, focal deficits, or increased intracranial pressure.
    • CT scans revealed evenly enhanced AVMs and ventricular dilatation in URAM, while RAMs were angiographically smaller than URAMs.

    Conclusions:

    • Clinical presentation significantly differs between ruptured and unruptured pediatric AVMs.
    • Early recognition of subtle URAM symptoms may aid in preventing catastrophic rupture.

    More Related Videos

    Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations14:58

    Comprehensive Endovascular and Open Surgical Management of Cerebral Arteriovenous Malformations

    Published on: October 20, 2017

    Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model05:12

    Induction and Micro-CT Imaging of Cerebral Cavernous Malformations in Mouse Model

    Published on: September 4, 2017

    Related Concept Videos

    The Arch of Aorta01:10

    The Arch of Aorta

    The coronary arteries, originating from the ascending aorta, bifurcate from two sinuses located within the ascending aorta. Positioned just above the aortic semilunar valve, these sinuses house essential aortic baroreceptors and chemoreceptors, crucial for maintaining cardiac function. The left coronary artery and the right coronary artery branch off from the left posterior and anterior aortic sinuses, respectively.
    Encircling the heart, the coronary arteries form a ring-like structure before...
    Arteries of the Head and Neck01:26

    Arteries of the Head and Neck

    The human body's intricate network of arteries ensures that every organ system receives the necessary oxygen and nutrients for optimal function. The arterial network in the head and neck region is particularly complex, providing vital blood flow to the brain, eyes, and other critical structures. Prominent arteries in this region include the internal carotid arteries and the vertebral arteries.
    The internal carotid arteries supply blood to the anterior portion of the cerebrum. They enter the...
    Hemorrhagic Stroke l: Introduction01:17

    Hemorrhagic Stroke l: Introduction

    A hemorrhagic stroke is an acute neurological event that occurs when a weakened cerebral blood vessel ruptures, allowing blood to accumulate within or around the brain. The sudden release of blood forms a focal hematoma that increases intracranial pressure, displaces neural tissue, and can obstruct cerebrospinal fluid pathways. These effects may be compounded by intraventricular extension of the hemorrhage, cerebral edema, or compression of adjacent structures, all of which contribute to...
    Cerebral Edema ll: Pathophysiology01:22

    Cerebral Edema ll: Pathophysiology

    Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this barrier loses...