Related Experiment Video
Updated: Sep 16, 2025

Modified Experimental Conditions for Noise-Induced Hearing Loss in Mice and Assessment of Hearing Function and Outer Hair Cell Damage
Published on: February 10, 2023
Role of risk factors and their variable types in predicting noise-induced hearing loss using artificial intelligence
Zhengheng Zhang1, Longteng Jiang2, Meibian Zhang1
1Chinese Center for Disease Control and Prevention, National Institute of Occupational Health and Poison Control, Beijing, China.
None:
Early prediction and warning of occupational noise-induced hearing loss (NIHL) in workers is critical. This study aimed to explore the role of risk factors and their variable types to NIHL prediction through machine learning (ML) techniques. Data on exposure and NIHL were sourced from the Chinese National Occupational Disease Surveillance Programs and field measurements involving 15,160 workers. We developed predictive models based on logistic regression, three tree-based algorithms (random forest [RF], extreme gradient boosting [XGBoost], light gradient boosting machine [LGBM]), and tabular neural network [TabNet]. Eight features, including age, sex, noise exposure duration (ED), A-weighted equivalent sound pressure (LAeq,8h), kurtosis, systolic blood pressure, diastolic blood pressure, and hearing protection device (HPD) usage, were evaluated through logistic regression and ML feature importance analyses. Models were trained using both original and categorized versions of the variables to compare the predictive value of variable types and assess the applicability of each algorithm. Multivariate logistic regression indicated that age, noise ED, LAeq,8h, sex, and HPD usage were significantly associated with NIHL (P < 0.05). Except for logistic regression, models built with original variable types using tree-based and TabNet algorithms outperformed those using categorized type (P < 0.05). The LGBM model utilizing original variable types, achieved the best performance on the test set [area under the curve (AUC) of 0.745 (95 % CI 0.729-0.763)]. Feature importance analysis revealed that LAeq,8h (LGBM), sex (XGBoost), age (RF), and kurtosis (TabNet) were key predictive variables, consistent with logistic regression results. Our study concludes that continuous variable type of risk factors provided superior predictive value compared to categorized type for NIHL. Tree-based and TabNet algorithms offer effective methods for assessing and predicting NIHL.

