Mapping regional disparities in testicular cancer mortality across Spain (2004-2023)

  • 0Servicio de Medicina Interna, Hospital Severo Ochoa, Leganés, Madrid, Spain.

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Summary

This summary is machine-generated.

Testicular cancer mortality in Spain is stable but shows significant regional differences. High-risk areas identified suggest potential disparities in healthcare access and environmental factors.

Area Of Science

  • Epidemiology
  • Spatial Analysis
  • Public Health

Background

  • Investigates testicular cancer (TC) mortality trends and spatial patterns in Spain.
  • Utilizes provincial-level spatial analysis to identify high-risk clusters.

Purpose Of The Study

  • To analyze testicular cancer mortality trends and spatial distribution across Spanish provinces.
  • To identify geographical areas with significantly higher TC mortality rates.

Main Methods

  • Ecological study using national TC mortality data (ICD-10 C62) from 2004-2023.
  • Calculated age-standardized mortality rates (ASMRs) and analyzed temporal trends using joinpoint regression.
  • Employed Bayesian hierarchical models and spatial clustering tests (Tango's, Kulldorff's) to assess spatial patterns and identify clusters.

Main Results

  • Recorded 909 TC deaths; ASMRs ranged from 0.14 to 0.26 per 1,000,000.
  • No significant temporal trends observed; age-specific mortality showed a bimodal distribution.
  • Identified elevated standardized mortality ratios (SMRs) in Zamora, Segovia, and Soria, and elevated relative risk in Badajoz, Huelva, and Sevilla. A high-mortality cluster was found in southwestern Spain.

Conclusions

  • Testicular cancer mortality in Spain is stable but exhibits significant regional disparities.
  • High-risk provinces and identified mortality clusters suggest potential inequalities in healthcare access, socioeconomic factors, and environmental exposures.

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