[Primary Malignant Melanoma Arising from the Anterior Urethra ; A Case Report]

A 67 year-old man consulted an urologist with the chief complaint of gross hematuria and discomfort in the urethral region. He was later diagnosed with malignant melanoma by transurethral biopsy. Urethrocystoscopy revealed lesions 3 cm peripherally from the sphincter muscle, and TUR of the urethra to the bladder neck revealed no malignant lesion in the prostatic area, urethra, or bladder. Radical penectomy was performed and the histopathologic diagnosis was pT2 malignant melanoma with negative urethral resection margins. At 9 months postoperatively, there was no evidence of recurrence or metastasis. Primary malignant melanoma of the urethra is an extremely rare disease with a poor prognosis for which no effective treatment has been established other than surgical resection. We report this case with discussion of the literature.