Related Experiment Video
Updated: Sep 16, 2025

DNA Origami-Mediated Substrate Nanopatterning of Inorganic Structures for Sensing Applications
Published on: September 27, 2019
Force-driven base recognition programs DNA origami-based supramolecular networks
Liqiong Niu1, Yuanyuan Luo1, Pengyan Hao1
1Institute of Analytical Chemistry and Instrument for Life Science, The Key Laboratory of Biomedical Information Engineering of Ministry of Education, School of Life Science and Technology, Xi'an Jiaotong University, Xianning West Road, Xi'an, Shaanxi 710049, P.R. China. wuna2017@xjtu.edu.cn.
Abstract:
This study proposes a force-driven recognition strategy that anchors conformationally constrained short loops at DNA origami edges, leveraging entropy compensation to enable large-scale nanostructure assembly. Precise thermoresponsive control across distinct temperature regimes is achieved by modulating nucleobase types and ultraviolet (UV) irradiation.

