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A Core Outcome Set for Stillbirth Care: An International Consensus Study.

Danya Bakhbakhi1, Anna Davies1, Dimitrios Siassakos2

  • 1Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.

BJOG : an International Journal of Obstetrics and Gynaecology
|July 7, 2025
PubMed
Summary
This summary is machine-generated.

A consensus study developed a core outcome set for stillbirth care, including maternal health, parental experience, and infant outcomes. This standardized set aims to improve research consistency and reduce bias in stillbirth studies.

Keywords:
consensus development studycore outcome setcore outcomesoutcome reporting biasstillbirth

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Area of Science:

  • Perinatal Medicine
  • Clinical Trial Methodology
  • Patient-Reported Outcomes

Background:

  • Stillbirth care research lacks standardized outcome measures.
  • Inconsistent outcome reporting hinders meta-analyses and research comparability.
  • A core outcome set is needed to improve the quality and impact of stillbirth research.

Purpose of the Study:

  • To develop a consensus-based core outcome set (COS) for stillbirth care.
  • To establish standardized outcomes for research and clinical trials in stillbirth.
  • To minimize outcome reporting bias and enhance comparability in stillbirth studies.

Main Methods:

  • International consensus development study involving 542 stakeholders.
  • Utilized a modified Delphi method and consensus meetings.
  • Included parents with lived experience and healthcare professionals.

Main Results:

  • Agreed upon 8 core outcomes for all stillbirth care studies (e.g., maternal complications, parental grief, mental health).
  • Identified 11 additional outcomes for specific research areas (e.g., cause of death, subsequent pregnancies, multiple births).
  • Outcomes cover maternal health, parental experience, infant outcomes, and specific stillbirth contexts.

Conclusions:

  • The developed core outcome set provides a standardized framework for stillbirth research.
  • Implementation can reduce outcome reporting bias and facilitate meta-analyses.
  • Aims to improve research efficiency and reduce wastage in stillbirth studies.