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A Core Outcome Set for Stillbirth Care: An International Consensus Study
Danya Bakhbakhi1, Anna Davies1, Dimitrios Siassakos2
1Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK.
Summary
A consensus study developed a core outcome set for stillbirth care, including maternal health, parental experience, and infant outcomes. This standardized set aims to improve research consistency and reduce bias in stillbirth studies.
Area of Science:
- Perinatal Medicine
- Clinical Trial Methodology
- Patient-Reported Outcomes
Background:
- Stillbirth care research lacks standardized outcome measures.
- Inconsistent outcome reporting hinders meta-analyses and research comparability.
- A core outcome set is needed to improve the quality and impact of stillbirth research.
Purpose of the Study:
- To develop a consensus-based core outcome set (COS) for stillbirth care.
- To establish standardized outcomes for research and clinical trials in stillbirth.
- To minimize outcome reporting bias and enhance comparability in stillbirth studies.
Main Methods:
- International consensus development study involving 542 stakeholders.
- Utilized a modified Delphi method and consensus meetings.
- Included parents with lived experience and healthcare professionals.
Main Results:
- Agreed upon 8 core outcomes for all stillbirth care studies (e.g., maternal complications, parental grief, mental health).
- Identified 11 additional outcomes for specific research areas (e.g., cause of death, subsequent pregnancies, multiple births).
- Outcomes cover maternal health, parental experience, infant outcomes, and specific stillbirth contexts.
Conclusions:
- The developed core outcome set provides a standardized framework for stillbirth research.
- Implementation can reduce outcome reporting bias and facilitate meta-analyses.
- Aims to improve research efficiency and reduce wastage in stillbirth studies.
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