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Sexual dysfunction in patients with inflammatory bowel disease.
Magdalena Kaniewska1, Konrad Lewandowski1, Dorota Szydlarska2,3
1Department of Gastroenterology and Internal Medicine, National Medical Institute of the Ministry of the Interior and Administration, Warsaw, Poland.
Przeglad Gastroenterologiczny
|July 7, 2025
Summary
Sexual dysfunction (SD) affects nearly half of inflammatory bowel disease (IBD) patients on biologics, driven by psychological factors, not disease severity. Comprehensive care for IBD patients must include sexual health support.
Area of Science:
- Gastroenterology
- Sexual Medicine
- Psychosomatic Medicine
Background:
- Inflammatory bowel diseases (IBD) significantly impact patients' quality of life, including sexual function.
- Data on sexual dysfunction (SD) and erectile dysfunction (ED) in IBD patients undergoing biological treatment are limited.
Purpose of the Study:
- To assess sexual function in IBD patients receiving biological therapy.
- To identify predictors of sexual dysfunction in this population.
Main Methods:
- A prospective study involving 135 adult IBD patients (Crohn's disease and ulcerative colitis) initiating biological treatment.
- Validated questionnaires, including the Female Sexual Function Index (FSFI) and International Index of Erectile Function-5 (IIEF-5), were used to evaluate sexual function.
Main Results:
- 43.7% of IBD patients reported sexual dysfunction, with no significant difference between men and women.
- Sexual dysfunction was correlated with self-reported limitations, particularly in women, but not with disease duration, medication type, or calprotectin levels.
- Psychological factors, not disease severity, were associated with SD and ED in patients on biologics.
Conclusions:
- Sexual dysfunction is prevalent in IBD patients on biological treatment and is linked to psychological factors.
- Disease severity and specific medications did not predict sexual dysfunction.
- Integrated care addressing both physical and psychological aspects of sexual health is crucial for IBD patients.
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