Sodium-glucose cotransporter-1 inhibition and depression: A Mendelian randomization study

Gang Fan1,2,3, Hong Zuo2, Xun Shi2

  • 1Clinical Research Center of Xianyang Central Hospital, Shaanxi Province, PR China.

SAGE Open Medicine
|July 7, 2025
PubMed
Summary

Sodium-glucose cotransporter-1 inhibition may reduce depression risk in Europeans, according to Mendelian randomization. Sodium-glucose cotransporter-2 inhibition showed no significant association with depression risk.

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