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Association Between Pulse Pressure and the Risk of Death Events - Beijing Municipality, China, 2010-2021
Yingqi Wei1, Kai Fang1, Rui Hou1
1Beijing Center for Disease Prevention and Control, Beijing, China.
China CDC Weekly
|July 7, 2025
Summary
Elevated pulse pressure (PP) indicates aortic stiffening and is linked to increased mortality risk. This risk is higher in women, older adults, and those who are overweight or obese, highlighting the need for targeted interventions.
Area of Science:
- Cardiovascular disease
- Hypertension research
- Public health
Background:
- Elevated pulse pressure (PP) is a known indicator of aortic stiffening.
- Aortic stiffening is associated with adverse clinical outcomes.
Purpose of the Study:
- To investigate the association between pulse pressure quartiles and mortality risk.
- To identify specific demographic groups with a higher risk associated with elevated PP.
Main Methods:
- Analysis of pulse pressure levels across different quartiles.
- Stratification of mortality risk based on PP quartiles.
- Examination of risk in subgroups including sex, age, and BMI.
Main Results:
- Mortality risk increased by 9.8%-23.9% in higher PP quartiles compared to the lowest (<40 mmHg).
- The association between elevated PP and mortality was more pronounced in females, adults aged 60-74 years, and overweight/obese individuals.
Conclusions:
- Elevated pulse pressure is a significant predictor of mortality.
- Specific populations, including women and older adults, are at higher risk.
- Early screening and management strategies for PP are crucial for public health.
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