Related Experiment Video
Updated: Jun 23, 2026

Surgical Swine Model of Chronic Cardiac Ischemia Treated by Off-Pump Coronary Artery Bypass Graft Surgery
Published on: March 27, 2018
Cardiac prognosis in noncardiac geriatric surgery
Insights
Simple exercise testing can predict heart complications in older adults undergoing surgery. Inability to exercise reliably identified patients at high risk for perioperative cardiac events.
Area of Science:
- Geriatric Medicine
- Cardiology
- Anesthesiology
Background:
- Perioperative cardiac complications pose a significant risk for older adults undergoing major surgery.
- Existing risk assessment tools, including clinical data and radionuclide ventriculography, have limitations in predicting these events.
Purpose of the Study:
- To identify reliable predictors of perioperative cardiac complications in patients aged 65 years or older undergoing elective surgery.
- To evaluate the predictive value of clinical assessment, traditional risk indices, and exercise radionuclide ventriculography.
Main Methods:
- An initial study assessed 100 geriatric patients using clinical data, electrocardiograms, laboratory tests, and radionuclide ventriculography.
- Multivariate analysis identified predictors of perioperative cardiac complications.
- A prospective study validated the findings in 55 additional patients.
Main Results:
- Thirteen patients experienced perioperative cardiac complications, with 6 deaths.
- Inability to perform 2 minutes of supine bicycle exercise to achieve a heart rate above 99 beats/min was a significant predictor (sensitivity 85%, specificity 64%).
- This exercise limitation provided predictive information not found in clinical or radionuclide data.
Conclusions:
- Simple exercise testing is a valuable tool for predicting perioperative cardiac complications in older surgical patients.
- Rest and exercise radionuclide ventriculography offered limited additional predictive information compared to basic exercise capacity.
- Inability to exercise independently predicts adverse cardiac outcomes in this population.
Abstract:
Predictors of perioperative complications, including cardiac death, ventricular tachycardia or fibrillation, and heart failure or myocardial infarction, were assessed in an initial study of 100 patients aged 65 years or older scheduled for elective abdominal or noncardiac thoracic surgery. Preoperative history, results of physical examination, chest roentgenogram, electrocardiogram, laboratory data, Dripps (American Society of Anesthesiologists) class, and Goldman cardiac risk index were compared with rest and exercise radionuclide ventriculograms. Thirteen patients had perioperative cardiac complications, and 6 died. Multivariate analysis showed that an inability to do 2 minutes of bicycle exercise in the supine position to raise the heart rate above 99 beats/min (sensitivity 85%, specificity 64%) gave predictive information not available from clinical or radionuclide data. On prospective testing involving 55 additional geriatric patients, inability to exercise was the only independent predictor of perioperative complications (p less than 0.05). Data from rest and exercise radionuclide ventriculography added little information for predicting perioperative cardiac risk.
Related Concept Videos
Cardiac Catheterization I: Pre-Procedure Overview
Cardiomyopathy II: Dilated Cardiomyopathy
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Cardiomyopathy V: Interprofessional Care
Cardiomyopathy VII: Pre and Post Operative Nursing Management
Aneurysm IV: Nursing Management

