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Related Concept Videos

Open Angle Glaucoma: Treatment01:27

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
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Related Experiment Video

Updated: Sep 16, 2025

A Rabbit Model of Aqueous-Deficient Dry Eye Disease Induced by Concanavalin A Injection into the Lacrimal Glands: Application to Drug Efficacy Studies
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Subconjunctival Steroids for Conjunctival Benign Reactive Lymphoid Hyperplasia.

Jai W Thompson1, Joseph Whitfield2, Lindsay A McGrath3,4

  • 1Sunshine Coast University Hospital, Birtinya, QLD, Australia.

Ocular Oncology and Pathology
|July 7, 2025
PubMed
Summary

Subconjunctival triamcinolone acetate effectively treated conjunctival benign reactive lymphoid hyperplasia (CBRLH), a rare condition. This approach led to complete lesion resolution and sustained remission in two patients, suggesting a potential standard of care.

Keywords:
Case seriesConjunctival benign reactive lymphoid hyperplasiaSubconjunctival triamcinolone acetate

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Area of Science:

  • Ophthalmology
  • Oncology
  • Immunology

Background:

  • Conjunctival benign reactive lymphoid hyperplasia (CBRLH) is a rare, benign lymphoproliferative disorder.
  • Current treatment standards for CBRLH are not established, necessitating exploration of therapeutic options.

Purpose of the Study:

  • To evaluate the efficacy of subconjunctival triamcinolone acetate in treating CBRLH.
  • To present a case series demonstrating a novel therapeutic approach for CBRLH.

Main Methods:

  • Two patients with CBRLH were treated with subconjunctival injections of triamcinolone acetate.
  • Clinical and histological examinations were performed to diagnose and monitor the condition.

Main Results:

  • Complete clinical resolution of CBRLH lesions was observed within three weeks post-treatment.
  • No recurrence of lesions was noted during a 12-month follow-up period.

Conclusions:

  • Subconjunctival triamcinolone acetate is an effective treatment for CBRLH.
  • This therapeutic approach offers rapid and sustained resolution, potentially guiding future management strategies for CBRLH.