Association Between Dietary Patterns and All-Cause Mortality in Individuals with Hypertension and Osteoporosis: A
Jianhua Guan1, Liang Ding1, Yifei Wang1
1Department of Orthopedics, Shanghai Jiao Tong University Affiliated Sixth People's Hospital South Campus (Shanghai Fengxian District Central Hospital), Shanghai, 201599, People's Republic of China.
Objective:
To explore the association of dietary patterns with all-cause mortality in individuals with hypertension and osteoporosis.
Methods:
Data on individuals aged ≥20 years who completed bone mineral density tests were retrieved from the National Health and Nutrition Examination Survey database. Three dietary patterns were Mediterranean Diet Score (MeDS), Alternative Health Eating Index (AHEI) and Dietary Approaches to Stop Hypertension (DASH). The relationships between osteoporosis (OS), hypertension (HTN) and all-cause mortality were assessed by multivariate and univariate Cox proportional hazard models, with hazard ratios (HRs) and confidence intervals (CIs). Interaction of OS and HTN on overall mortality was evaluated by the attributable proportion (AP), relative excess risk due to interaction (RERI), and synergy index (S). Associations of three dietary patterns with all-cause mortality were explored in different groups, including adults with HTN or OS only, and adults with or without OS and HTN. Subgroups of gender and menopausal state were further evaluated these associations.
Results:
Of the total 16,358 participants, 1383 (5.84%) died during the follow-up duration. Participants who had HTN (HR=1.272, 95% CI: 1.083-1.494) or OS (HR=1.674, 95% CI: 1.262-2.221) had a higher risk of overall mortality. There was an interaction between HTN and OS on overall mortality (RERI=0.677, 95% CI: 0.070-1.285; AP=0.293, 95% CI: 0.094-0.492; SI=2.070, 95% CI: 1.124-3.813). The AHEI-2010, MeDS, and DASH were related to overall mortality in individuals with OS and HTN. The MeDS and DASH were concerned with all-cause mortality in HTN patients without OS. The MeDS and AHEI-2010 were linked to overall mortality in adults without OS and HTN.
Conclusion:
The impacts of different dietary patterns were differences in multi-feature population. It was suggested that reasonable dietary management is beneficial to the prognosis of different populations.
More Related Videos
07:22Glycemic Impact on Knee Osteoarthritis Symptoms on Physical, Radiographic, and Inflammatory Markers among Individuals Aged 50 and Over with Diabetes
Published on: March 7, 2025
04:46'Boden Food Plate': Novel Interactive Web-based Method for the Assessment of Dietary Intake
Published on: September 18, 2018
Related Concept Videos
01:20Study Designs in Epidemiology
Observational studies are those where the researcher does not intervene but rather observes natural variations. They include cross-sectional, cohort, and...
01:29Bone Disorders
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
01:29Hypertension II: Pathophysiology
01:30Hypertension III: Clinical Manifestations and Diagnostic Studies
01:18Hypertension and Regulation of Blood Pressure
01:28Hypertension IV: Drug Therapy and Lifestyle Modifications