Related Experiment Video
Updated: Sep 16, 2025
28:13
Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
Published on: February 26, 2013
33.5K
Sepsis-induced Atrial Fibrillation: Can We Predict and Prevent This High-Risk Complication?
Vahagn Tamazyan1, Aleksan Khachatryan2, Ashot Batikyan3
1Department of Internal Medicine, Maimonides Medical Center, Brooklyn, USA.
Cureus
|July 7, 2025
Summary
Sepsis-induced new-onset atrial fibrillation (NOAF) is a serious complication predicting long-term heart issues and stroke. This review explores NOAF
Area of Science:
- Critical care medicine
- Cardiology
- Epidemiology
Background:
- Sepsis-induced new-onset atrial fibrillation (NOAF) is a common complication in critically ill patients, associated with adverse outcomes.
- NOAF predicts long-term cardiovascular risks, including recurrent arrhythmias and thromboembolic events.
- Uncertainty surrounds anticoagulation use in sepsis-induced NOAF due to bleeding risks and unclear guidelines.
Purpose of the Study:
- To review the current evidence on sepsis-induced NOAF.
- To focus on stroke prevention, recurrence, and anticoagulation challenges.
- To examine emerging predictive models and prevention strategies.
Main Methods:
- Literature review of existing studies on sepsis-induced NOAF.
- Consolidation of evidence regarding pathophysiology, incidence, risk factors, and clinical impact.
- Analysis of data related to stroke prevention, recurrence, and anticoagulation.
Main Results:
- Sepsis-induced NOAF is linked to increased morbidity, mortality, stroke, and hospitalization.
- Recurrence rates for NOAF exceed 50% over five years, with a heightened risk of stroke.
- The role and efficacy of anticoagulation in sepsis-induced NOAF require further investigation.
Conclusions:
- Sepsis-induced NOAF is a significant predictor of future cardiovascular events and stroke.
- Effective stroke prevention and management strategies for this patient group are needed.
- Targeting inflammatory and hemodynamic pathways may offer novel prevention strategies for NOAF.
Related Concept Videos
01:29Venous Thrombosis III: Interprofessional Care
26
Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
26
01:25Dysrhythmias VI: Management of Dysrhythmias
110
Dysrhythmia management involves a multifaceted approach, incorporating pharmacological treatments, medical procedures, surgical interventions, lifestyle modifications, and patient education.Pharmacological ManagementAntiarrhythmic Drugs:Class I (Sodium Channel Blockers): This class includes quinidine and procainamide, which reduce the speed of impulse conduction in the heart, stabilize the cardiac membrane, and control arrhythmias. Quinidine and procainamide are Class IA agents that prolong the...
110
01:18Endocarditis III: Medical Management
22
Infective endocarditis management involves a multifaceted approach encompassing infection prevention, lifestyle modifications, pharmacological therapy, and surgical management.Infection Prevention:Hand Hygiene: Thorough handwashing is crucial to prevent the spread of infection. Hand hygiene should be performed regularly, especially before and after using the restroom.Oral Hygiene: Good oral hygiene is essential. It includes brushing teeth immediately after waking up and before bed, flossing...
22
01:30Acute Kidney Injury IV: Diagnostic Studies and Prevention
59
Accurate diagnosis and effective prevention are critical in managing Acute Kidney Injury (AKI), which is linked to high mortality rates ranging from 10% to 80%. Timely recognition of at-risk patients and careful monitoring can significantly reduce the likelihood of kidney damage.Diagnostic Assessments:The diagnostic process starts with a comprehensive medical history to identify prerenal, intrarenal, and postrenal causes.Prerenal causes, such as dehydration, hypotension, or blood loss, should...
59
01:25ECG Interpretation of Arrhythmias II: Atrial, Junctional and Ventricular Arrhythmias
170
Arrhythmia is a condition characterized by an irregular heart rhythm, with ECG changes that differ based on its origin and nature. The types of arrhythmias discussed below include atrial, junctional, and ventricular arrhythmias.Atrial ArrhythmiasPremature Atrial Complexes (PACs): PACs are early atrial beats caused by stress, caffeine, alcohol, electrolyte imbalances, hypoxia, hyperthyroidism, or certain medications (e.g., bronchodilators and decongestants). The ECG shows early P waves with an...
170
01:22Healthcare Associated Infections II: Preventive Measures
2.8K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.8K